Apamin

CAS 24345-16-2C79H131N31O24S4Cell Biology

Apamin (CAS 24345-16-2) is a bioactive peptide with the molecular formula C79H131N31O24S4 and a molecular weight of 2027.34 g/mol. Synthetically derived, Apamin is known for its potent activity as a blocker of small conductance calcium-activated potassium channels (SK channels). This characteristic makes it a valuable research tool in neuroscience and cell biology for investigating ion channel function and cellular signaling pathways.

Email us

Apamin (C79H131N31O24S4) — chemical structure, CAS 24345-16-2; Life Science, fine chemical supplied by Tech Serve Solutions

AN-AZBeeBioactive Small MoleculesCell BiologyIon ChannelsMonovalent Ion ChannelsPeptides and ProteinsPeptides for Cell BiologyPotassium Channel ModulatorsToxins and Venoms

01 /Applications

Neuroscience Research

Apamin serves as a crucial pharmacological tool for researchers studying the role of SK channels in neuronal excitability, synaptic plasticity, and central nervous system functions. Its specific channel blocking activity aids in dissecting complex neural circuits.

Cell Biology Studies

In cell biology, Apamin is used to investigate the involvement of calcium-activated potassium channels in various cellular processes, including cell proliferation, differentiation, and apoptosis. It helps in understanding ion transport mechanisms.

Ion Channel Pharmacology

As a selective SK channel blocker, Apamin is indispensable for pharmacological studies aimed at understanding the structure-function relationships of ion channels and for validating potential drug targets related to these channels.

02 /Properties

Molecular weight	2027.34
Empirical formula	C79H131N31O24S4
Assay	≥95% (HPLC)
Storage temperature	−20°C
Biological source	synthetic

03 /Safety & handling

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Danger

Hazard statements

H334May cause allergy or asthma symptoms if inhaled

Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

24345-16-2

MDL number

MFCD00167944

05 /Additional specifications

Gene Information	rat ... Kcnn1(54261)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Apamin used for?

Apamin is primarily used as a research tool in neuroscience and cell biology to specifically block small conductance calcium-activated potassium channels (SK channels), aiding in the study of ion channel function and cellular signaling.

What is the CAS number and formula for Apamin?

The CAS number for Apamin is 24345-16-2, and its empirical formula is C79H131N31O24S4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Apamin with a purity of ≥95% as determined by HPLC. This product is intended for research purposes and is not represented as USP, BP, EP, or other pharmacopoeial grades.

How should Apamin be handled and stored?

Apamin is classified as hazardous, indicated by GHS08 (Health Hazard) and a Danger signal word, with hazard statement H334 (May cause allergy or asthma symptoms or breathing difficulties if inhaled). It requires careful handling to avoid inhalation. Store at -20°C.