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Acetyltrimethylsilane

CAS 13411-48-8(CH3)3SiCOCH3Chemical Synthesis

Acetyltrimethylsilane (CAS: 13411-48-8), with the linear formula (CH3)3SiCOCH3, is an organosilicon compound with a molecular weight of 116.23 g/mol. It functions as a valuable reagent in organic synthesis, particularly in organometallic chemistry. This compound is utilised for introducing the trimethylsilylacetyl group and in various functional group transformations.

IUPAC
1-(Trimethylsilyl)ethanone
Synonyms
1-(Trimethylsilyl)ethanone
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Acetyltrimethylsilane ((CH3)3SiCOCH3) — chemical structure, CAS 13411-48-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical SynthesisOrganometallic ReagentsOrganosiliconOthers
01 /Applications

Organic Synthesis Reagent

Acetyltrimethylsilane serves as a versatile reagent in organic synthesis. It is employed in reactions requiring the introduction of the trimethylsilylacetyl moiety or for specific functional group manipulations.

Organosilicon Chemistry

As an organosilicon compound, it finds application in studies and syntheses within organosilicon chemistry. Its structure allows for unique reactivity patterns characteristic of silicon-containing molecules.

Intermediate in Chemical Manufacturing

This compound can act as an intermediate in the multi-step synthesis of more complex organic molecules, contributing to the development of novel chemical entities.

02 /Properties
Molecular weight116.23
Linear formula(CH3)3SiCOCH3
Assay97%
Density0.811 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.411(lit.)
Storage temperature2-8°C
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H225Highly flammable liquid and vapour
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point8 °C / 46.4 °F
Transport (UN / ADR)UN 1993BF 3 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)F,Xi
Risk statements (R)11-36/37/38
Safety statements (S)16-26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
13411-48-8
MDL number
MFCD00134244
PubChem substance
24862334
Beilstein registry
2071361
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Acetyltrimethylsilane used for?

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Acetyltrimethylsilane is primarily used as a reagent in organic synthesis, particularly for introducing the trimethylsilylacetyl group and in various transformations within organometallic and organosilicon chemistry.

What is the CAS number and formula for Acetyltrimethylsilane?

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The CAS number for Acetyltrimethylsilane is 13411-48-8, and its linear formula is (CH3)3SiCOCH3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Acetyltrimethylsilane with an assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.

How should Acetyltrimethylsilane be handled safely?

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Acetyltrimethylsilane is a flammable liquid and vapour (H225) and can cause skin (H315), serious eye (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, in a well-ventilated area, away from ignition sources.

Is Acetyltrimethylsilane shipped internationally?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and can arrange for the shipment of Acetyltrimethylsilane worldwide.

How can I request a sample or quote for Acetyltrimethylsilane?

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To request a sample or obtain a quote for Acetyltrimethylsilane, please contact our sales department via the website or email.

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