Acetyl chloride
Acetyl chloride (CAS 75-36-5), with the linear formula CH3COCl and a molecular weight of 78.50 g/mol, is a reactive acyl halide. This colourless liquid is a key reagent in organic synthesis, primarily used for acetylation reactions. Its high reactivity makes it valuable for introducing the acetyl group into various organic molecules across diverse chemical industries. Proper handling is essential due to its hazardous nature.
Organic Synthesis Reagent
Acetyl chloride is extensively employed in organic chemistry for the preparation of esters and amides through acylation reactions. It serves as a fundamental building block for introducing the acetyl functional group into more complex molecular structures.
Pharmaceutical Intermediate Production
In the pharmaceutical sector, acetyl chloride acts as a crucial intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its ability to efficiently acetylate allows for the modification and creation of complex drug molecules.
Dye and Pigment Manufacturing
This compound finds application in the chemical industry for the synthesis of certain dyes and pigments. Its reactive nature facilitates the chemical transformations required to produce specific chromophoric systems.
Laboratory Research
Acetyl chloride is a common reagent in research laboratories for a wide range of chemical transformations and synthetic studies. Its predictable reactivity makes it a reliable tool for chemists exploring new molecular pathways.
| Molecular weight | 78.50 |
|---|---|
| Linear formula | CH3COCl |
| Assay | 98% |
| Boiling point | 52 °C(lit.) |
| Density | 1.104 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.389(lit.) |
| Vapour pressure | 11.69 psi (20 °C)32.33 psi (55 °C) |
| Melting point | −112 °C(lit.) |
| Vapour density | 2.7 (vs air) |
| Autoignition temp | 1353 °F |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 5 °C / 41 °F |
|---|---|
| Transport (UN / ADR) | UN 1717 8(3) / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-34 |
| Safety statements (S) | 9-16-26-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Acetyl Chloride (CAS 75-36-5) used for?
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Acetyl chloride (CAS 75-36-5) is a key reagent in organic synthesis, primarily used for acetylation reactions to introduce the acetyl group into molecules, and serves as an intermediate in the production of pharmaceuticals, dyes, and other fine chemicals.
What is the CAS number and chemical formula for Acetyl Chloride?
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The CAS number for Acetyl Chloride is 75-36-5, and its linear chemical formula is CH3COCl.
What grade and purity does Tech Serve Solutions supply for Acetyl Chloride?
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Tech Serve Solutions supplies Acetyl Chloride with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
What are the primary safety hazards associated with Acetyl Chloride?
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Acetyl chloride is highly flammable (H225) and causes severe skin burns and eye damage (H314). It reacts violently with water. Handling requires strict safety precautions, including appropriate personal protective equipment and working in a well-ventilated area, away from ignition sources and water.
How is Acetyl Chloride packed, shipped, and exported by TSS?
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Tech Serve Solutions exports Acetyl Chloride, packed in compliance with international regulations for hazardous materials. Specific packaging details are available upon request for shipment and export inquiries.
How can I request a quote or sample for Acetyl Chloride?
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To request a quote or sample for Acetyl Chloride, please contact our sales department through the website or provide your requirements via the dedicated inquiry form.
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