Acetic acid-2-13C
Acetic acid-2-13C (CAS 1563-80-0; formula 13CH3CO2H; molar mass 61.04 g/mol) is a stable-isotope-labelled form of glacial acetic acid in which the methyl (C-2) carbon is enriched with carbon-13, supplied at 99 atom % 13C. It is a colourless, corrosive liquid (boiling point 117-118 °C, density 1.066 g/mL) used chiefly as a tracer in NMR, metabolic and mechanistic studies and as a labelled building block in synthesis. Tech Serve Solutions supplies it to research and analytical laboratories worldwide.
- IUPAC
- 13C Labeled acetic acid,Glacial acetic acid-2-13C
- Synonyms
- Acetic acid-2-13CGlacial acetic acid-2-13C13C-labelled acetic acidAcetic acid (methyl-13C)13CH3CO2HCAS 1563-80-0
Stable-isotope tracer studies
The 13C label at the C-2 (methyl) position makes this compound a metabolic and biochemical tracer, allowing acetate uptake and downstream metabolism to be followed by mass spectrometry and NMR.
13C NMR and mechanistic research
Carbon-13 enrichment greatly enhances the methyl-carbon signal in NMR, supporting reaction-mechanism, kinetic and structural investigations where the position of the label must be tracked.
Isotopically labelled synthesis
It serves as a labelled building block for preparing 13C-enriched acetyl groups, acetates and other derivatives used in chemical and pharmaceutical research.
MRI/MRS and imaging research
As an isotopically labelled organic acid it is used in magnetic resonance spectroscopy and related imaging research where 13C-acetate is employed as a metabolic probe.
Analytical reference standard
The defined isotopic purity makes it suitable as an internal standard or reference material in quantitative isotope-ratio and tracer analyses.
| Molecular weight | 61.04 |
|---|---|
| Linear formula | 13CH3CO2H |
| Boiling point | 117-118 °C(lit.) |
| Density | 1.066 g/mL at 25 °C |
| Refractive index | n20/D 1.372(lit.) |
| Melting point | 16.2 °C(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 40 °C / 104 °F |
|---|---|
| Transport (UN / ADR) | UN 2789 8/PG 2 |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-35 |
| Safety statements (S) | 23-26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Isotopic Purity | 99 atom % 13C |
|---|---|
| Mol Wt | mol wt 61.04 by atom % calculation |
| Mass Shift | M+1 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Acetic acid-2-13C used for?
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It is used mainly as a carbon-13 stable-isotope tracer in 13C NMR, metabolic, mechanistic and MRI/MRS research, and as a labelled building block for synthesising 13C-enriched acetyl groups and acetate derivatives. The label sits on the C-2 (methyl) carbon.
What is the CAS number and molecular formula of Acetic acid-2-13C?
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The CAS number is 1563-80-0 and the molecular formula is 13CH3CO2H, with the carbon-13 enrichment on the methyl (C-2) carbon. The molecular weight is 61.04 g/mol (by atom % calculation) and the MDL number is MFCD00074856.
What grade and purity does Tech Serve Solutions supply?
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It is supplied as a research-grade stable-isotope reagent with an isotopic purity of 99 atom % 13C (mass shift M+1). We supply it for research and analytical use and do not represent it as a USP, BP, EP or other pharmacopoeial grade unless agreed in writing.
What are the safety and handling requirements for Acetic acid-2-13C?
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It is classified as a flammable liquid and as causing severe skin burns and eye damage (GHS02, GHS05; signal word Danger; H226, H314). Handle with chemical-resistant gloves, eye protection and adequate ventilation, away from heat and ignition sources; on contact rinse skin and eyes and seek medical attention. The flash point is about 40 °C.
How is Acetic acid-2-13C packed, shipped and exported?
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As a corrosive, flammable liquid it is classified for transport under UN 2789, Class 8, Packing Group II, and is supplied in suitable sealed, isotope-grade containers with full documentation. We export worldwide in compliance with applicable dangerous-goods regulations; pack sizes are quoted on request.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, and we will provide a quotation, available documentation and lead time. Sample availability for this stable-isotope reagent is confirmed on enquiry.
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