8-Quinolinyl trifluoromethanesulfonate
8-Quinolinyl trifluoromethanesulfonate (CAS: 108530-08-1), with the molecular formula C10H6F3NO3S and a molecular weight of 277.22 g/mol, is a high-purity chemical supplied by Tech Serve Solutions. This compound serves as a valuable reagent in organic synthesis, particularly in palladium-catalyzed reactions. It is a key building block for creating complex molecular structures, finding applications in pharmaceutical research and advanced chemical manufacturing.
- IUPAC
- 8-Quinolinyl triflate

Palladium-Catalyzed Arylation Reactions
This triflate is employed as an electrophile in palladium-catalyzed β-arylation reactions. It is specifically noted for its use in the arylation of modified vinyl ethers, enabling the formation of new carbon-carbon bonds.
Organic Synthesis Building Block
As a functionalized quinoline derivative, 8-Quinolinyl trifluoromethanesulfonate acts as a versatile building block. Its triflate leaving group facilitates various coupling reactions and transformations in synthetic organic chemistry.
Research and Development
This compound is utilized in academic and industrial research laboratories for the development of novel synthetic methodologies and the exploration of new chemical entities. Its defined structure aids in predictable reaction outcomes.
| Molecular weight | 277.22 |
|---|---|
| Empirical formula | C10H6F3NO3S |
| Assay | 97% |
| Application | Employed in the palladium-catalyzed β-arylation of modified vinyl ethers.1 |
| Melting point | 65-68 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 8-Quinolinyl trifluoromethanesulfonate used for?
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8-Quinolinyl trifluoromethanesulfonate (CAS: 108530-08-1) is primarily used as a reagent in palladium-catalyzed β-arylation reactions, especially with modified vinyl ethers, and as a versatile building block in organic synthesis.
What are the CAS number and formula for 8-Quinolinyl trifluoromethanesulfonate?
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The CAS number is 108530-08-1 and the empirical formula (Hill Notation) is C10H6F3NO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 8-Quinolinyl trifluoromethanesulfonate with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmaceutical grade.
How should 8-Quinolinyl trifluoromethanesulfonate be handled safely?
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8-Quinolinyl trifluoromethanesulfonate is a Warning compound classified with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Handle with appropriate personal protective equipment, including Eyeshields, Gloves, and a dust mask type N95 (US). Ensure adequate ventilation, and avoid breathing dust. In case of contact, rinse eyes thoroughly with water and seek medical advice if irritation persists.
Is 8-Quinolinyl trifluoromethanesulfonate a controlled substance?
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Based on the provided data, there is no indication that 8-Quinolinyl trifluoromethanesulfonate is a controlled substance.
How is 8-Quinolinyl trifluoromethanesulfonate packed and shipped?
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8-Quinolinyl trifluoromethanesulfonate is carefully packed to ensure integrity during transport. As a global supplier and exporter, Tech Serve Solutions adheres to all regulations for shipping chemicals internationally.
How can I request a quote or sample?
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To request a quote or a sample of 8-Quinolinyl trifluoromethanesulfonate, please contact our sales team through the website or by phone. Our experts will assist you promptly.
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