8-Hydroxy-5-nitroquinoline
8-Hydroxy-5-nitroquinoline (CAS 4008-48-4, C9H6N2O3) is a fine chemical compound with a molecular weight of 190.16 g/mol. It serves as a valuable building block in chemical synthesis, particularly within the realm of heterocyclic chemistry. This compound is primarily utilised for its reactive properties in the development of new molecules and materials, contributing to advancements in various scientific research areas.
- IUPAC
- 5-Nitro-8-quinolinol

Synthesis of Chelating Agents
8-Hydroxy-5-nitroquinoline has been employed in the synthesis of novel 8-hydroxyquinoline chelating agents. These agents are designed for specific applications, including their solubility in CO2, which opens avenues for unique chemical processes and analyses.
Heterocyclic Building Block
As a heterocyclic building block, this compound is integral to the construction of more complex organic molecules. Its structure lends itself to derivatisation, enabling chemists to introduce specific functionalities and properties into target compounds.
Chemical Synthesis Intermediate
This chemical acts as an intermediate in various organic synthesis pathways. Researchers utilise it to create diverse chemical entities for applications ranging from materials science to medicinal chemistry research.
| Molecular weight | 190.16 |
|---|---|
| Empirical formula | C9H6N2O3 |
| Assay | 96% |
| Solubility | alcohol: very slightly solublediethyl ether: very slightly solublehydrochloric acid: freely soluble (hot) |
| Application | 8-Hydroxy-5-nitroquinoline was used in the synthesis of novel CO2-soluble 8-hydroxyquinoline chelating agents1. |
| Melting point | 181-183 °C(lit.) |

Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H331Toxic if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P311Call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-36/37/38 |
| Safety statements (S) | 26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 8-Hydroxy-5-nitroquinoline used for?
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8-Hydroxy-5-nitroquinoline is used as a building block in chemical synthesis, notably in the creation of novel CO2-soluble 8-hydroxyquinoline chelating agents.
What are the CAS number and formula for 8-Hydroxy-5-nitroquinoline?
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The CAS number for 8-Hydroxy-5-nitroquinoline is 4008-48-4, and its empirical formula is C9H6N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 8-Hydroxy-5-nitroquinoline with an assay of 96%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the primary safety concerns when handling 8-Hydroxy-5-nitroquinoline?
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8-Hydroxy-5-nitroquinoline is classified as toxic if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges, is essential. Handle in a well-ventilated area.
How is 8-Hydroxy-5-nitroquinoline typically packed and shipped?
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As a global supplier and exporter, Tech Serve Solutions ensures that 8-Hydroxy-5-nitroquinoline is packed and shipped in compliance with all relevant regulations for hazardous materials.
How can I request a sample or quote for 8-Hydroxy-5-nitroquinoline?
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To request a sample or a quote for 8-Hydroxy-5-nitroquinoline, please contact the Tech Serve Solutions sales team through our website or direct inquiry channels.
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