7-Methoxycoumarin-4-acetic acid
7-Methoxycoumarin-4-acetic acid (CAS 62935-72-2) is a heterocyclic organic compound with the molecular formula C12H10O5. This coumarin derivative serves as a valuable building block in chemical synthesis. It is primarily recognised for its utility as a fluorescent probe and label in biochemical research, particularly in the preparation of modified peptides and proteins. Its structure facilitates incorporation into various molecular systems for tracking and detection purposes.
- IUPAC
- 7-Methoxy-2-oxo-2H-1-benzopyran-4-acetic acid
Fluorescent Probe Development
7-Methoxycoumarin-4-acetic acid is employed in the synthesis of fluorescent probes, such as selectively labelled fluorescent derivatives of human insulin. This application leverages its intrinsic fluorescence properties for biological imaging and analysis.
Peptide Labelling
The compound has been utilised as a fluorescent label for peptides. Its incorporation allows for enhanced visualisation and tracking of peptides in biological systems and during synthesis processes.
Bioconjugation Reagent
It serves as a reagent in the preparation of modified peptides, including cell-penetrating peptides like transportan 10. This demonstrates its role in creating functionalised biomolecules for research.
| Molecular weight | 234.20 |
|---|---|
| Empirical formula | C12H10O5 |
| Assay | 97% |
| Solubility | DMF: soluble50 mg/mL, clear, colorless to yellow |
| Application | 7-Methoxycoumarin-4-acetic acid has been used:• as fluorescent probe in preparation of two novel LysB29 selectively labelled fluorescent derivatives of human insulin1• in the preparation of cell-penetrating peptide transportan 10 (tp10)2• as fluorescent label for peptides3 |
| Melting point | 193 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 87 °C / 188.6 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7-Methoxycoumarin-4-acetic acid used for?
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7-Methoxycoumarin-4-acetic acid is used as a fluorescent probe and label in biochemical research, particularly for preparing fluorescently labelled peptides and proteins, and as a building block in chemical synthesis.
What are the CAS number and molecular formula for 7-Methoxycoumarin-4-acetic acid?
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The CAS number is 62935-72-2, and the molecular formula is C12H10O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 7-Methoxycoumarin-4-acetic acid with an assay of 97%. This product is intended for research and technical use and is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling recommendations for this compound?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. In environments with potential vapour exposure, a half-mask respirator (EU/US) or a multi-purpose combination respirator cartridge (US) is recommended. The compound has a flash point of 87 °C (188.6 °F) and is classified under WGK Germany 3, indicating it is hazardous to water.
How is 7-Methoxycoumarin-4-acetic acid typically packed and shipped?
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As a specialist global supplier, Tech Serve Solutions ensures products like 7-Methoxycoumarin-4-acetic acid are appropriately packed for safe transit and export, adhering to international shipping regulations for chemicals.
How can I request a quote or sample?
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To request a quote or a sample of 7-Methoxycoumarin-4-acetic acid, please contact our sales team through the website or by phone, providing the product name and CAS number (62935-72-2).
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