6-Hydroxymelatonin
6-Hydroxymelatonin (CAS 2208-41-5), with the molecular formula C13H16N2O3, is a bioactive small molecule and a key metabolite of melatonin. It plays a role in biological processes related to cell signaling and neurobiology. This compound is often utilized in research settings for studies in cell biology, neuroscience, and as a GPCR modulator, contributing to a deeper understanding of physiological pathways.
- IUPAC
- 3-(N-Acetylaminoethyl)-6-hydroxy-5-methoxyindole

Neuroscience Research
Used in studies investigating neurological pathways and the function of melatonin receptors, particularly MTNR1A and MTNR1B in humans.
Cell Signaling Studies
Applied in research to explore cellular responses and signaling cascades influenced by melatonin and its metabolites.
Biochemical Investigations
Serves as a biochemical reagent for understanding metabolic processes and the biological activity of indole derivatives.
GPCR Modulation Research
Employed to study the modulation of G protein-coupled receptors, offering insights into receptor pharmacology.
| Molecular weight | 248.28 |
|---|---|
| Empirical formula | C13H16N2O3 |
| Solubility | alcohol: soluble |


Hazard statements
- H302Harmful if swallowed
- H351Suspected of causing cancer
Precautionary statements
- P281Use personal protective equipment as required
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-40 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... MTNR1A(4543), MTNR1B(4544) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Hydroxymelatonin used for?
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6-Hydroxymelatonin (CAS 2208-41-5) is primarily used in research settings for studies in neuroscience, cell biology, cell signaling, and as a GPCR modulator.
What are the CAS number and molecular formula for 6-Hydroxymelatonin?
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The CAS number for 6-Hydroxymelatonin is 2208-41-5, and its molecular formula is C13H16N2O3.
What grade and purity does Tech Serve Solutions supply for 6-Hydroxymelatonin?
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Tech Serve Solutions supplies 6-Hydroxymelatonin with a purity typically specified by the batch certificate of analysis. It is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety and handling precautions for 6-Hydroxymelatonin?
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6-Hydroxymelatonin is classified with a 'Warning' signal word and carries hazard statements H302 (Harmful if swallowed) and H351 (Suspected of causing cancer). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection (type N100 or P3 filters), should be used. Handle with caution and avoid exposure. Consult the SDS for detailed information.
How is 6-Hydroxymelatonin typically packed and shipped?
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6-Hydroxymelatonin is carefully packed according to industry standards to ensure safe transit and is available for global export.
How can I request a sample or quote for 6-Hydroxymelatonin?
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To request a sample or a quotation for 6-Hydroxymelatonin, please contact our sales team through the website or by direct enquiry, providing your specific requirements.
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