6-Hydroxydopamine hydrobromide
6-Hydroxydopamine hydrobromide (CAS 636-00-0) is a chemical compound with the linear formula (HO)<sub>3</sub>C<sub>6</sub>H<sub>2</sub>CH<sub>2</sub>CH<sub>2</sub>NH<sub>2</sub> · HBr and a molecular weight of 250.09 g/mol. This light brown, purum grade substance is primarily employed as a selective neurotoxin in neuroscience research to induce Parkinsonian symptoms in animal models. It serves as a valuable tool for studying dopaminergic pathways and neurodegenerative diseases.
- IUPAC
- 2,4,5-Trihydroxyphenethylamine hydrobromide,2,5-Dihydroxytyramine hydrobromide,2-(2,4,5-Trihydroxyphenyl)ethylamine hydrobromide,6-OHDA
- Synonyms
- 2,4,5-Trihydroxyphenethylamine hydrobromide2,5-Dihydroxytyramine hydrobromide2-(2,4,5-Trihydroxyphenyl)ethylamine hydrobromide6-OHDA
Neuroscience Research
Utilised extensively in research to selectively destroy dopaminergic neurons in the brain. This application aids in the study of Parkinson's disease pathogenesis and the development of potential therapeutic strategies.
Dopaminergic System Studies
Serves as a critical reagent for investigating the function and integrity of the dopaminergic system. Researchers use it to model dopamine depletion and observe compensatory mechanisms.
Pharmacological Tool
Employed as a pharmacological tool to induce models of neurodegeneration, facilitating the screening and evaluation of neuroprotective agents and novel drug candidates.
| Molecular weight | 250.09 |
|---|---|
| Linear formula | (HO)3C6H2CH2CH2NH2 · HBr |
| Assay | 95% |
| Grade | purum |
| Colour | light brown |
| Storage temperature | −20°C |
| Melting point | 216-220 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Hydroxydopamine hydrobromide used for?
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6-Hydroxydopamine hydrobromide is primarily used in neuroscience research as a selective neurotoxin to destroy dopaminergic neurons, aiding in the study of Parkinson's disease and related neurodegenerative conditions.
What are the CAS number and chemical formula for 6-Hydroxydopamine hydrobromide?
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The CAS number is 636-00-0, and the linear formula is (HO)<sub>3</sub>C<sub>6</sub>H<sub>2</sub>CH<sub>2</sub>CH<sub>2</sub>NH<sub>2</sub> · HBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 6-Hydroxydopamine hydrobromide at a purum grade with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should 6-Hydroxydopamine hydrobromide be handled safely?
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Handle with care using appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Avoid inhalation, skin, and eye contact. It is classified as an irritant (H315, H319, H335).
How is 6-Hydroxydopamine hydrobromide stored and shipped?
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It is recommended to store 6-Hydroxydopamine hydrobromide at -20°C. TSS exports fine chemicals globally, ensuring proper packaging and adherence to international shipping regulations.
How can I request a quote or sample for 6-Hydroxydopamine hydrobromide?
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To request a quote or sample, please contact our sales team via the website or direct email, providing your specific requirements and shipping details.
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