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6-Cyano-2-naphthol

CAS 52927-22-7NCC10H6OHChemical Synthesis

6-Cyano-2-naphthol (CAS: 52927-22-7; Formula: NCC10H6OH) is a key organic building block with a molecular weight of 169.18 g/mol. This nitrile and nitrogen compound is primarily utilised as a reactant in various catalysed organic synthesis reactions. Its defined structure and chemical properties make it valuable in the development of more complex molecules within the pharmaceutical and chemical industries.

IUPAC
2-Cyano-6-hydroxynaphthalene,2-Hydroxy-6-naphthonitrile,2-Cyano-6-naphthol,6-Cyano-2-hydroxynaphthalene,6-Hydroxy-2-naphthalenecarbonitrile,6-Hydroxy-2-naphthonitrile
Synonyms
2-Cyano-6-hydroxynaphthalene2-Hydroxy-6-naphthonitrile2-Cyano-6-naphthol6-Cyano-2-hydroxynaphthalene6-Hydroxy-2-naphthalenecarbonitrile6-Hydroxy-2-naphthonitrile
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6-Cyano-2-naphthol (NCC10H6OH) — chemical structure, CAS 52927-22-7; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC10 to C27Chemical SynthesisCyanides/NitrilesNitrogen Compounds
01 /Applications

Palladium-Catalyzed Reductions

6-Cyano-2-naphthol serves as a substrate in palladium-catalyzed reduction reactions, enabling specific chemical transformations in organic synthesis pathways.

Nickel-Catalyzed Cross-Coupling

This compound is employed as a reactant in nickel-catalyzed cross-coupling reactions, facilitating the formation of carbon-carbon bonds in complex molecular assemblies.

Palladium-Catalyzed Heck Reactions

It functions as a participant in palladium-catalyzed Heck reactions, a widely used method for creating substituted alkenes.

02 /Properties
Molecular weight169.18
Linear formulaNCC10H6OH
Assay97%
ApplicationReactant for:• Palladium-catalyzed reduction1• Nickel-catalyzed cross-coupling reactions2• Palladium-catalyzed Heck reactions3
Melting point165.5-170.5 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
52927-22-7
MDL number
MFCD01863480
PubChem substance
24877738
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 6-Cyano-2-naphthol primarily used for?

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6-Cyano-2-naphthol is used as a reactant in palladium-catalyzed reductions, nickel-catalyzed cross-coupling reactions, and palladium-catalyzed Heck reactions.

What are the CAS number and chemical formula for 6-Cyano-2-naphthol?

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The CAS number for 6-Cyano-2-naphthol is 52927-22-7, and its chemical formula is NCC10H6OH.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 6-Cyano-2-naphthol with an assay of 97%. This product is not represented as USP, BP, EP, or pharmacopoeia grade.

How should 6-Cyano-2-naphthol be handled safely?

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According to GHS, 6-Cyano-2-naphthol is a Warning substance (H315, H319, H335) causing skin irritation, serious eye irritation, and respiratory irritation. Handle with a dust mask type N95, eyeshields, and gloves in a well-ventilated area. Avoid breathing dust.

How is 6-Cyano-2-naphthol packed, shipped, and exported?

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Tech Serve Solutions professionally packs, ships, and exports 6-Cyano-2-naphthol globally, adhering to all relevant regulations for chemical transport.

How can I request a sample or quote for 6-Cyano-2-naphthol?

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To request a sample or a quotation for 6-Cyano-2-naphthol, please contact the Tech Serve Solutions sales team via our website or direct inquiry.

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