6-Carboxy-4′,5′-dichloro-2′,7′-dimethoxyfluorescein N-hydroxysuccinimide ester
6-Carboxy-4′,5′-dichloro-2′,7′-dimethoxyfluorescein N-hydroxysuccinimide ester (CAS: 113394-23-3) is a specialised biochemical reagent with the empirical formula C27H17Cl2NO11 and a molecular weight of 602.33 g/mol. This fluorescein derivative serves as a fluorescent label and probe, primarily utilised in biological and chemical research for applications requiring sensitive detection and visualisation. Its structure allows for conjugation to biomolecules, facilitating studies in cell biology and related fields.
- IUPAC
- 6-JOE SE
- Synonyms
- 113394-23-3, C27H17Cl2NO11, 6-JOE SE

Fluorescent Labeling
This compound acts as a fluorescent label, enabling the attachment of a detectable marker to various biomolecules or substrates. Its dichlorodimethoxyfluorescein moiety provides fluorescent properties for tracking and quantification in assays.
Cell Biology Research
Utilised as a fluorescent probe in cell biology, it can be employed to study cellular processes, localisation of molecules, or to visualise cellular structures. The NHS ester facilitates conjugation to amine groups found in proteins and other biological molecules.
Biochemical Assays
This reagent is suitable for use in various biochemical assays where fluorescence detection is required. The N-hydroxysuccinimide ester is a reactive group that readily forms stable amide bonds with primary amines.
| Molecular weight | 602.33 |
|---|---|
| Empirical formula | C27H17Cl2NO11 |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | mol wt 602.34 |
|---|---|
| Shipped In | wet ice |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-Carboxy-4′,5′-dichloro-2′,7′-dimethoxyfluorescein N-hydroxysuccinimide ester used for?
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This compound is primarily used as a fluorescent label and probe in biochemical and cell biology research. Its NHS ester functionality allows for conjugation to biomolecules, facilitating their detection and visualisation through fluorescence.
What are the CAS number and empirical formula?
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The CAS number for 6-Carboxy-4′,5′-dichloro-2′,7′-dimethoxyfluorescein N-hydroxysuccinimide ester is 113394-23-3. The empirical formula is C27H17Cl2NO11.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a research-grade chemical. We do not represent it as USP, BP, EP, or other pharmacopoeial grades. Purity information can be found on the Certificate of Analysis.
How should this product be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter such as type N95 (US) or P1 (EN143) is recommended. Store at -20°C, and note that it is shipped on wet ice.
Is this compound a controlled substance?
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The provided data does not indicate that this compound is a controlled substance.
How can I request a sample or quote?
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To request a sample or a quote, please contact our sales department via the website or by phone, providing the product name and CAS number.
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