6-(4-Boc-piperazin-1-yl)pyridine-3-boronic acid pinacol ester
6-(4-Boc-piperazin-1-yl)pyridine-3-boronic acid pinacol ester (CAS: 496786-98-2; C20H32BN3O4) is a heterocyclic organoboron compound with a molecular weight of 389.30 g/mol. This compound is primarily utilised as a building block in organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura coupling. Its structure, featuring a pyridine ring substituted with a piperazine moiety and a boronic ester, makes it valuable for constructing complex molecules in pharmaceutical and materials science research.
- IUPAC
- 4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)-1-Boc-piperazine
Suzuki-Miyaura Coupling Reagent
This pinacol boronate ester is an effective coupling partner in palladium-catalysed Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds with aryl or vinyl halides. It is widely employed in the synthesis of biaryl compounds and other complex organic structures.
Pharmaceutical Intermediate
The compound serves as a key intermediate in the synthesis of potential drug candidates. Its pyridine and piperazine functionalities, along with the reactive boronate ester group, allow for diverse derivatisation strategies in medicinal chemistry.
Materials Science Research
This molecule can be incorporated into the development of novel organic materials. Its structure may contribute to the unique electronic or optical properties of polymers or small molecules used in advanced material applications.
Heterocyclic Chemistry Synthesis
As a functionalised heteroaryl boronic ester, it is a valuable reagent for introducing complex heterocyclic fragments into organic molecules. This facilitates the exploration of novel chemical spaces in drug discovery and beyond.
| Molecular weight | 389.30 |
|---|---|
| Empirical formula | C20H32BN3O4 |
| Assay | 96% |
| Melting point | 165-169 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 6-(4-Boc-piperazin-1-yl)pyridine-3-boronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions and as an intermediate in the preparation of complex molecules for pharmaceutical research and materials science.
What is the CAS number and molecular formula?
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The CAS number is 496786-98-2 and the molecular formula is C20H32BN3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 96%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with a WGK (Germany) of 3, indicating a high hazard to water.
How is this chemical packed and shipped?
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This chemical is carefully packed and exported by Tech Serve Solutions, adhering to international shipping regulations for chemical compounds.
How can I request a sample or quote for this product?
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Please contact our sales team through our website or by phone to request a sample or a quotation for 6-(4-Boc-piperazin-1-yl)pyridine-3-boronic acid pinacol ester.
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