5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-D-ribonic acid γ-lactone
5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-D-ribonic acid γ-lactone (CAS 75467-36-6) is a protected carbohydrate derivative with the molecular formula C14H26O5Si and a molecular weight of 302.44. This compound serves as a valuable intermediate in complex organic synthesis, particularly within carbohydrate chemistry and the development of novel chemical entities. Its specific structural features make it useful for introducing protected ribose moieties in multi-step synthetic routes.
- Synonyms
- C14H26O5Si

Carbohydrate Synthesis
Utilised as a building block in the synthesis of complex carbohydrates and nucleoside analogues due to its protected hydroxyl groups and lactone functionality.
Organic Synthesis Intermediate
Serves as a versatile intermediate in multi-step organic synthesis, enabling the controlled introduction of specific stereochemical features derived from ribose.
Chemical Biology Research
Applied in research settings for the creation of modified carbohydrates or probes for investigating biological processes at the molecular level.
Pharmaceutical Intermediate
Potentially used in the early stages of drug discovery and development where complex carbohydrate structures are required for therapeutic agents.
| Molecular weight | 302.44 |
|---|---|
| Empirical formula | C14H26O5Si |
| Assay | 97% |
| Optical activity | [α]20/D −47°, c = 0.8 in chloroform |
| Melting point | 72-74 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-D-ribonic acid γ-lactone used for?
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This compound is primarily used as an intermediate in organic synthesis, particularly in carbohydrate chemistry and the development of complex molecules. It is valuable for introducing protected ribose units in multi-step synthetic pathways.
What is the CAS number and molecular formula for 5-O-(tert-Butyldimethylsilyl)-2,3-O-isopropylidene-D-ribonic acid γ-lactone?
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The CAS number is 75467-36-6 and the molecular formula is C14H26O5Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent it as USP, BP, EP or other pharmacopoeia grades unless explicitly stated.
What are the safety and handling recommendations for this compound?
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This compound is classified as a Warning. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.
How is this chemical shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product is carefully packaged to ensure safe transit and compliance with international shipping regulations.
How can I request a sample or a quote for this product?
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To request a sample or a quote, please contact our sales team directly through the website or by phone, providing the product name and CAS number (75467-36-6).
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