5-Isopropyl-2-methoxyphenylboronic acid
5-Isopropyl-2-methoxyphenylboronic acid (CAS: 216393-63-4, Formula: C10H15BO3, MW: 194.04) is a valuable aryl boronic acid derivative utilised in advanced chemical synthesis. This compound serves as a key reactant in the development of diverse biologically active molecules, including potential therapeutic agents for atherosclerosis and cancer. Its utility extends to organometallic reactions like the Suzuki-Miyaura cross-coupling, facilitating the construction of complex organic structures.
- IUPAC
- 5-Isopropyl-2-methoxybenzeneboronic acid,[2-Methoxy-5-(1-methylethyl)phenyl]boronic acid
- Synonyms
- [2-Methoxy-5-(1-methylethyl)phenyl]boronic acid
Synthesis of Oxazolidinones
Serves as a reactant in the preparation of oxazolidinones, which are investigated as cholesteryl ester transfer protein (CETP) inhibitors for the treatment of atherosclerosis.
Development of CHK1 Inhibitors
Utilised in the synthesis of selective quinazolinyl-phenol inhibitors of CHK1, explored for their potential as antitumor agents and radioprotectants.
Preparation of Biaryl Carbamates
Acts as a precursor in the synthesis of biaryl-containing carbamates, which have been studied as CETP inhibitors.
Synthesis of MMP Inhibitors
Employed in the preparation of α-sulfone hydroxamates, a class of compounds investigated as matrix metalloproteinase (MMP) inhibitors.
Suzuki-Miyaura Cross-Coupling
A key reactant in Suzuki-Miyaura cross-coupling reactions with 2-nitroarenediazonium tetrafluoroborate, enabling the synthesis of 2-nitrobiphenyls.
| Molecular weight | 194.04 |
|---|---|
| Empirical formula | C10H15BO3 |
| Storage temperature | 2-8°C |
| Application | Reactant involved in the synthesis of many biologically active molecules including:• Oxazolidinones for use as cholesteryl ester transfer protein inhibitors for atherosclerosis treatment1,2• Selective quinazolinyl-phenol inhibitors of CHK1 as antitumor and radioprotectants3• Biaryl-containing carbamates as CETP inhibitors4• α -Sulfone hydroxamates as MMP inhibitors5Reactant involved in Suzuki-Miyaura cross coupling with 2-nitroarenediazonium tetrafluoroborate for synthesis of 2-nitrobiphenyls6 |
| Melting point | 84-88 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Isopropyl-2-methoxyphenylboronic acid used for?
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5-Isopropyl-2-methoxyphenylboronic acid is used as a reactant in the synthesis of biologically active molecules, including potential treatments for atherosclerosis and cancer, and in Suzuki-Miyaura cross-coupling reactions.
What is the CAS number and formula for 5-Isopropyl-2-methoxyphenylboronic acid?
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The CAS number is 216393-63-4 and the empirical formula is C10H15BO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. We do not represent it as USP, BP, EP, or other pharmacopoeia grades. Please refer to the Certificate of Analysis for specific purity details.
How should 5-Isopropyl-2-methoxyphenylboronic acid be handled and stored?
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This compound is classified under GHS hazard category 3 for water hazard. It should be stored at 2-8°C. Handle with appropriate personal protective equipment in a well-ventilated area.
Is this chemical shipped internationally?
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Yes, Tech Serve Solutions specialises in global supply and export of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote?
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Please use the contact form on our website or call our sales team to request a sample or obtain a quotation for 5-Isopropyl-2-methoxyphenylboronic acid.
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