5-Iodovanillin
5-Iodovanillin (CAS: 5438-36-8), with the molecular formula IC6H2(OCH3)(OH)CHO and a molecular weight of 278.04 g/mol, is a valuable organic building block. This substituted benzaldehyde is primarily utilised in organic synthesis for the preparation of more complex molecules. Its structure, featuring an iodine atom and a vanillin core, makes it a useful intermediate in pharmaceutical and fine chemical research and development.

Intermediate in Organic Synthesis
5-Iodovanillin serves as a key intermediate in the synthesis of various organic compounds. Its reactive iodine and aldehyde functionalities allow for diverse chemical transformations, making it suitable for constructing complex molecular architectures in multi-step syntheses.
Synthesis of Pharmaceutical Agents
This compound has been employed in the synthesis of specific pharmaceutical agents. For instance, it was used in the preparation of platelet activating factor antagonists, contributing to the development of potential therapeutic compounds.
Characterisation Studies
5-Iodovanillin has been utilised in chemical characterisation studies. It was previously used in the characterisation of 5-Iodoacetovanillone, aiding in the structural elucidation and verification of related compounds.
| Molecular weight | 278.04 |
|---|---|
| Linear formula | IC6H2(OCH3)(OH)CHO |
| Assay | 97% |
| Application | 5-Lodovanillin was used in the characterization of 5-Iodoacetovanillone1. 5-Iodovanillin has also been used in the synthesis of platelet activating factor antagonist L-659,9892. |
| Melting point | 183-185 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Iodovanillin used for?
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5-Iodovanillin is primarily used as an intermediate in organic synthesis, including the preparation of pharmaceutical agents and in chemical characterisation studies.
What are the CAS number and chemical formula for 5-Iodovanillin?
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The CAS number for 5-Iodovanillin is 5438-36-8, and its chemical formula is IC6H2(OCH3)(OH)CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Iodovanillin with a minimum assay of 97%. This product is supplied for research and laboratory use; TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary safety concerns when handling 5-Iodovanillin?
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5-Iodovanillin is classified as an irritant. It can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and a dust mask (type N95 or equivalent), should be used during handling.
How is 5-Iodovanillin packaged and exported by TSS?
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Tech Serve Solutions ensures that 5-Iodovanillin is carefully packaged to maintain its integrity during transit. We are experienced in exporting fine chemicals globally to meet the needs of research institutions and industrial clients worldwide.
How can I request a sample or a quote for 5-Iodovanillin?
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To request a sample or obtain a quotation for 5-Iodovanillin, please contact our sales department via the website or direct email, providing your specific requirements and delivery details.
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