5-Fluoro-2-(trifluoromethyl)benzoic acid

CAS 654-99-9FC6H3(CF3)CO2HChemical Synthesis

5-Fluoro-2-(trifluoromethyl)benzoic acid (CAS 654-99-9) is a fluorinated organic compound with the molecular formula FC6H3(CF3)CO2H and a molecular weight of 208.11 g/mol. This benzoic acid derivative serves as a valuable building block in organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals. Its trifluoromethyl and fluorine substituents offer unique electronic properties, making it a key intermediate for introducing these functionalities into target molecules. TSS supplies this chemical for research and development purposes.

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5-Fluoro-2-(trifluoromethyl)benzoic acid (FC6H3(CF3)CO2H) — chemical structure, CAS 654-99-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksCarbonyl CompoundsCarboxylic AcidsChemical SynthesisFluorinated Building BlocksOrganic Building BlocksTrifluoromethyl More...

01 /Applications

Pharmaceutical Intermediate

Utilised in the synthesis of active pharmaceutical ingredients (APIs), leveraging its fluorinated aromatic structure for drug discovery and development.

Agrochemical Synthesis

Serves as a precursor for the creation of new pesticides, herbicides, and other crop protection agents due to the enhanced biological activity often conferred by fluorinated moieties.

Materials Science

Can be incorporated into the design of advanced materials where specific electronic or thermal properties are desired.

Organic Synthesis Building Block

A versatile reagent for introducing fluoro- and trifluoromethyl-substituted phenyl rings into complex organic molecules during synthetic pathways.

02 /Properties

Molecular weight	208.11
Linear formula	FC6H3(CF3)CO2H
Assay	98%
Melting point	80-83 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

654-99-9

MDL number

MFCD00083521

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 5-Fluoro-2-(trifluoromethyl)benzoic acid used for?

5-Fluoro-2-(trifluoromethyl)benzoic acid is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and advanced materials.

What is the CAS number and molecular formula for 5-Fluoro-2-(trifluoromethyl)benzoic acid?

The CAS number is 654-99-9, and the molecular formula is FC6H3(CF3)CO2H.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 5-Fluoro-2-(trifluoromethyl)benzoic acid with an assay of 98%. We do not represent this product as USP, BP, or EP grade.

How should 5-Fluoro-2-(trifluoromethyl)benzoic acid be handled?

This compound is a Warning hazard, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment including Eyeshields, Gloves, and a dust mask type N95 (US). Ensure adequate ventilation.