5-Chloro-2-methoxyphenylboronic acid
5-Chloro-2-methoxyphenylboronic acid (CAS: 89694-48-4) is an organoboron compound with the formula ClC6H3(OCH3)B(OH)2. It serves as a valuable intermediate in organic synthesis. This disubstituted aryl boronic acid is primarily utilised as a reactant in cross-coupling reactions such as the Suzuki-Miyaura coupling and Boron-Heck arylation, enabling the formation of new carbon-carbon bonds.
- IUPAC
- 2-Methoxy-5-chlorophenylboronic acid,3-Chloro-6-methoxyphenylboronic acid
- Synonyms
- 2-Methoxy-5-chlorophenylboronic acid3-Chloro-6-methoxyphenylboronic acid
Suzuki-Miyaura Coupling Reactions
This boronic acid is a key building block in Suzuki-Miyaura coupling reactions. It facilitates the formation of biaryl compounds, which are common motifs in pharmaceuticals and advanced materials.
Boron-Heck Arylation
It acts as a reactant in Boron-Heck arylation, a palladium-catalysed cross-coupling reaction. This application allows for the introduction of aryl groups onto olefinic substrates.
Synthesis of Complex Organic Molecules
As a versatile organometallic reagent, it finds application in the multi-step synthesis of complex organic molecules, including potential drug candidates and agrochemicals.
| Molecular weight | 186.40 |
|---|---|
| Linear formula | ClC6H3(OCH3)B(OH)2 |
| Application | Reactant for:• Boron-Heck arylation1• Suzuki-Miyaura reaction2 |
| Melting point | 134-141 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Chloro-2-methoxyphenylboronic acid used for?
+
5-Chloro-2-methoxyphenylboronic acid is used as a reactant in organic synthesis, specifically for Boron-Heck arylation and Suzuki-Miyaura cross-coupling reactions.
What are the CAS number and formula for 5-Chloro-2-methoxyphenylboronic acid?
+
The CAS number is 89694-48-4 and the chemical formula is ClC6H3(OCH3)B(OH)2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 5-Chloro-2-methoxyphenylboronic acid. The specific grade and purity are available upon request, and TSS does not represent this product as USP, BP, or EP grade.
How should 5-Chloro-2-methoxyphenylboronic acid be handled?
+
Appropriate personal protective equipment, including eyeshields and gloves, should be worn when handling. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the safety data sheet for full handling instructions.
Is 5-Chloro-2-methoxyphenylboronic acid a controlled substance?
+
The provided data does not indicate that 5-Chloro-2-methoxyphenylboronic acid is a controlled substance.
How is this product shipped and exported?
+
Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Details regarding specific shipping and export procedures for 5-Chloro-2-methoxyphenylboronic acid can be provided upon enquiry.
How can I request a sample or quote?
+
To request a sample or a quotation for 5-Chloro-2-methoxyphenylboronic acid, please contact the Tech Serve Solutions sales team through our website or direct contact channels.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis