5-Amino-2-fluoropyridine
5-Amino-2-fluoropyridine (CAS: 1827-27-6), with the molecular formula C5H5FN2 and a molecular weight of 112.11 g/mol, is a vital fluorinated heterocyclic building block. This compound serves as a key intermediate in the synthesis of complex organic molecules, particularly within the pharmaceutical and agrochemical industries. Its structure, featuring both an amino group and a fluorine atom on a pyridine ring, allows for diverse chemical transformations, making it a valuable reagent for advanced chemical research and development.
- IUPAC
- 6-Fluoro-3-pyridineamine
- Synonyms
- 6-Fluoro-3-pyridineamine

Pharmaceutical Synthesis
Used as a critical building block in the synthesis of active pharmaceutical ingredients (APIs). The fluoropyridine moiety can be incorporated to modulate drug properties such as metabolic stability and binding affinity.
Agrochemical Development
Serves as an intermediate in the creation of novel agrochemicals, including herbicides, insecticides, and fungicides. Fluorinated heterocycles are frequently employed to enhance efficacy and environmental profiles.
Organic Synthesis
A versatile reagent for constructing complex heterocyclic systems. It is valuable for introducing the 2-fluoropyridin-5-yl group in various organic transformations and for developing new chemical entities.
Materials Science Research
Explored as a precursor for specialised materials where the unique electronic and physical properties of fluorinated aromatic compounds are desired.
| Molecular weight | 112.11 |
|---|---|
| Empirical formula | C5H5FN2 |
| Assay | 97% |
| Melting point | 87-91 °C |


Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Amino-2-fluoropyridine primarily used for?
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5-Amino-2-fluoropyridine (CAS: 1827-27-6) is primarily used as a building block in the synthesis of pharmaceuticals and agrochemicals, and in general organic synthesis.
What are the CAS number and molecular formula for 5-Amino-2-fluoropyridine?
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The CAS number is 1827-27-6 and the molecular formula is C5H5FN2.
What grade and purity does Tech Serve Solutions supply for 5-Amino-2-fluoropyridine?
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Tech Serve Solutions supplies 5-Amino-2-fluoropyridine with a minimum assay of 97%. This product is intended for research and development purposes and is not represented as USP, BP, EP, or any pharmacopoeia grade.
What are the safety considerations when handling 5-Amino-2-fluoropyridine?
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5-Amino-2-fluoropyridine is classified as Dangerous. It causes skin irritation (H315), serious eye damage (H318), and may cause respiratory irritation (H335). Always handle with appropriate personal protective equipment (gloves, eye protection, respiratory protection) in a well-ventilated area, following all safety data sheet guidelines.
How is 5-Amino-2-fluoropyridine packed and exported?
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Tech Serve Solutions securely packs and exports 5-Amino-2-fluoropyridine according to international shipping regulations for chemical compounds, ensuring safe transit globally.
How can I request a quote or sample for 5-Amino-2-fluoropyridine?
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To request a quote or sample of 5-Amino-2-fluoropyridine, please visit the product page on the Tech Serve Solutions website and use the online inquiry form or contact our sales department directly.
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