5-Amino-2-chloropyridine
5-Amino-2-chloropyridine (CAS: 5350-93-6), with the molecular formula C5H5ClN2 and a molecular weight of 128.56 g/mol, is a halogenated heterocyclic building block. It serves as a key intermediate in organic synthesis, particularly in the development of pharmaceutical compounds and functional materials. Its structure allows for diverse chemical modifications, making it valuable in research and development for creating novel molecules with specific properties. TSS supplies this compound with a minimum assay of 98%.

Pharmaceutical Intermediate
Used in the synthesis of complex pharmaceutical agents, including potential drug candidates. For instance, it has been employed in the preparation of [2H5]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Analytical Chemistry
Applied in the development of analytical methods and materials for impurity detection. It was utilized in the identification and evaluation of molecularly imprinted polymers for the selective removal of aminopyridine impurities from pharmaceutical products.
Organic Synthesis
Serves as a versatile building block in general organic synthesis due to its reactive amino and chloro functional groups on the pyridine ring.
| Molecular weight | 128.56 |
|---|---|
| Empirical formula | C5H5ClN2 |
| Assay | 98% |
| Application | 5-Amino-2-chloropyridine was used in the synthesis of [2H5]2-amino-l-methyl-6-phenylimidazo[4,5-b]pyridine1. It was used in identification and evaluation of molecularly imprinted polymers for the selective removal of potentially genotoxic aminopyridine impurities from pharmaceuticals2. |
| Melting point | 81-83 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Amino-2-chloropyridine used for?
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5-Amino-2-chloropyridine is primarily used as a building block in organic synthesis, particularly for creating pharmaceutical intermediates and in analytical chemistry for developing methods to detect impurities.
What are the CAS number and formula for 5-Amino-2-chloropyridine?
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The CAS number for 5-Amino-2-chloropyridine is 5350-93-6, and its empirical formula is C5H5ClN2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Amino-2-chloropyridine with a minimum assay of 98%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the main safety hazards associated with 5-Amino-2-chloropyridine?
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5-Amino-2-chloropyridine is classified with a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used during handling.
How is 5-Amino-2-chloropyridine typically shipped or exported?
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As a global supplier and exporter of fine chemicals, Tech Serve Solutions handles the packaging and export of 5-Amino-2-chloropyridine in compliance with international shipping regulations for chemical substances.
How can I request a sample or quote for 5-Amino-2-chloropyridine?
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To request a sample or a quote for 5-Amino-2-chloropyridine, please contact the Tech Serve Solutions sales team through our website or by phone.
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