5-Amino-1-ethylpyrazole
5-Amino-1-ethylpyrazole (CAS: 3528-58-3; Formula: C5H9N3; MW: 111.15) is a versatile heterocyclic building block. This pyrazole derivative is primarily used in chemical synthesis, particularly for the preparation of more complex heterocyclic structures such as 1-protected-1H-pyrazolo[3,4-b]pyridines. Its well-defined structure and reactivity make it a valuable intermediate for researchers and chemists in organic synthesis and medicinal chemistry.

Synthesis of Pyrazolo[3,4-b]pyridines
5-Amino-1-ethylpyrazole serves as a key precursor in the synthesis of 1-protected-1H-pyrazolo[3,4-b]pyridines. This application is important in the development of novel heterocyclic compounds for various research purposes.
Heterocyclic Building Block
As a functionalised pyrazole, this compound acts as a fundamental building block in organic chemistry. It enables the construction of diverse molecular architectures containing the pyrazole core.
Chemical Synthesis Intermediate
This chemical is employed as an intermediate in multi-step syntheses. Its specific functional groups allow for controlled chemical transformations and the introduction of the pyrazole moiety into larger molecules.
| Molecular weight | 111.15 |
|---|---|
| Empirical formula | C5H9N3 |
| Assay | 99% |
| Boiling point | 92-94 °C/0.01 mmHg(lit.) |
| Application | 5-Amino-1-ethylpyrazole is a heterocyclic building block1, has been used in the preparation of 1-protected-1H-pyrazolo[3,4-b]pyridines2. |
| Melting point | 52-57 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Amino-1-ethylpyrazole used for?
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5-Amino-1-ethylpyrazole is primarily used as a heterocyclic building block in chemical synthesis, notably for preparing compounds like 1-protected-1H-pyrazolo[3,4-b]pyridines.
What is the CAS number and formula for 5-Amino-1-ethylpyrazole?
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The CAS number is 3528-58-3 and the empirical formula is C5H9N3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Amino-1-ethylpyrazole with a purity of 99%. This product is supplied for research and development purposes; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling precautions for 5-Amino-1-ethylpyrazole?
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5-Amino-1-ethylpyrazole is a Warning substance (GHS07) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be used. Ensure good ventilation. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection.
How is 5-Amino-1-ethylpyrazole packed and shipped?
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Tech Serve Solutions securely packs and exports 5-Amino-1-ethylpyrazole, adhering to all relevant shipping regulations for chemical substances.
How can I request a quote or sample of 5-Amino-1-ethylpyrazole?
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To request a quote or sample of 5-Amino-1-ethylpyrazole, please contact our sales team through the website or by phone, providing your contact details and the quantity required.
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