(4S-trans)-2,2-Dimethyl-α,α,α′,α′-tetra(1-naphthyl)-1,3-dioxolane-4,5-dimethanol
(4S-trans)-2,2-Dimethyl-α,α,α′,α′-tetra(1-naphthyl)-1,3-dioxolane-4,5-dimethanol (CAS: 171086-52-5) is a specialized organic compound with the molecular formula C47H38O4. This chiral reagent, weighing 666.80 g/mol, is a valuable tool in asymmetric synthesis. It is specifically employed as a reagent for the highly enantioselective addition of primary alkyl Grignard reagents to ketones, enabling precise stereochemical control in chemical transformations.
- Synonyms
- α′,α′-tetra(1-naphthyl)-1,3-dioxolane-4,5-dimethanol171086-52-5C47H38O4
Enantioselective Grignard Additions
This compound serves as a critical reagent for the highly enantioselective addition of primary alkyl Grignard reagents to ketones. It facilitates the formation of chiral products with controlled stereochemistry.
Chiral Ligand in Asymmetric Synthesis
As a TADDOL derivative, it functions as a chiral ligand or auxiliary in asymmetric synthesis. Its structure allows for effective induction of chirality in various organic reactions.
Chemical Synthesis Research
Used in research laboratories for developing novel synthetic methodologies and exploring stereoselective reactions. Its specific application lies in complex molecule synthesis where enantiopurity is paramount.
| Molecular weight | 666.80 |
|---|---|
| Empirical formula | C47H38O4 |
| Assay | 99% |
| Optical activity | [α]20/D +280°, c = 1 in ethyl acetate |
| Application | Reagent for the highly enantioselective addition of primary alkyl Grignards to ketones.1 |
| Melting point | 200 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (4S-trans)-2,2-Dimethyl-α,α,α′,α′-tetra(1-naphthyl)-1,3-dioxolane-4,5-dimethanol used for?
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This compound is primarily used as a reagent for the highly enantioselective addition of primary alkyl Grignards to ketones, playing a crucial role in asymmetric synthesis.
What are the CAS number and molecular formula?
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The CAS number is 171086-52-5, and the molecular formula is C47H38O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 99%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the safety and handling precautions?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. The compound has a GHS classification indicated by WGK Germany 3, signifying a hazard to water.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, handling packing, shipping, and export with professional expertise.
How can I request a sample or quote for this chemical?
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Please contact our sales team directly to request a sample or obtain a quotation for this product.
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