(4S)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-5,5-dimethyl-4-(1-methylethyl)-oxazole
(4S)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-5,5-dimethyl-4-(1-methylethyl)-oxazole (CAS 1152313-76-2) is a chiral organophosphorus compound with the molecular formula C26H28NOP and a molecular weight of 401.48 g/mol. This PHOX ligand is recognised for its utility in asymmetric synthesis, serving as a crucial component in developing stereoselective catalytic processes. It is supplied by TSS at an assay of 97%.
- IUPAC
- (S)-2-(2-(Diphenylphosphino)phenyl)-4-isopropyl-5,5-dimethyl-4,5-dihydrooxazole,(S)-5,5-(Dimethyl)-i-Pr-PHOX
- Synonyms
- 1152313-76-2C26H28NOP(S)-2-(2-(Diphenylphosphino)phenyl)-4-isopropyl-5,5-dimethyl-4,5-dihydrooxazole(S)-5,5-(Dimethyl)-i-Pr-PHOX
![(4S)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-5,5-dimethyl-4-(1-methylethyl)-oxazole (C26H28NOP) — chemical structure, CAS 1152313-76-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F1152313-76-2.png&w=3840&q=75)
Asymmetric Catalysis
This chiral oxazoline-phosphine ligand is employed in metal-catalyzed asymmetric reactions to achieve high enantioselectivity. It facilitates the synthesis of chiral molecules, which are vital in pharmaceuticals and fine chemicals.
Ligand for Transition Metal Complexes
It functions as a privileged ligand in coordination chemistry, forming complexes with transition metals. These complexes are active catalysts in various organic transformations, promoting stereospecific bond formations.
Chemical Synthesis Reagent
Used in advanced organic synthesis, this compound enables the development of novel synthetic routes and the efficient preparation of complex chemical structures. Its PHOX scaffold is a well-established motif in catalysis.
| Molecular weight | 401.48 |
|---|---|
| Empirical formula | C26H28NOP |
| Assay | 97% |
| Melting point | 124-128 °C |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38-53 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (4S)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-5,5-dimethyl-4-(1-methylethyl)-oxazole used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis and chemical synthesis to facilitate stereoselective reactions.
What is the CAS number and molecular formula for this oxazole derivative?
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The CAS number is 1152313-76-2, and the molecular formula is C26H28NOP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at an assay of 97%. It is suitable for research and chemical synthesis purposes. TSS does not represent this product as USP, BP, or EP grade.
How should this chemical be handled safely?
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This compound is toxic if swallowed and causes skin and eye irritation, and may cause respiratory irritation. It should be handled with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling instructions and emergency procedures. (GHS06, Danger: H301, H315, H319, H335, H413).
Is this compound subject to any special shipping or handling regulations?
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Yes, this compound is classified as toxic (UN 2811 6.1 / PGIII). Shipping and handling must comply with relevant dangerous goods regulations. TSS exports globally, adhering to all international shipping standards.
How can I request a sample or quote for this product?
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To request a sample or a quotation, please contact our sales team via the website or by phone, providing the product name and CAS number (1152313-76-2).
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