4-Butoxy-2,3,5,6-tetrafluorophenylboronic acid
4-Butoxy-2,3,5,6-tetrafluorophenylboronic acid (CAS: 871126-19-1; C10H11BF4O3) is a versatile organoboron compound with a molecular weight of 266.00. This pentasubstituted aryl boronic acid derivative is a key building block in organic synthesis. It is frequently employed in cross-coupling reactions, particularly Suzuki-Miyaura couplings, for the formation of carbon-carbon bonds. Its unique fluorinated aromatic structure allows for the synthesis of complex molecules with tailored electronic and steric properties, finding utility in materials science and pharmaceutical research.
- Synonyms
- 6-tetrafluorophenylboronic acid871126-19-1C10H11BF4O3
Suzuki-Miyaura Coupling Reagent
4-Butoxy-2,3,5,6-tetrafluorophenylboronic acid is widely used as a coupling partner in palladium-catalyzed Suzuki-Miyaura reactions. This enables the efficient synthesis of biaryl compounds and other complex organic structures.
Intermediate in Organic Synthesis
The compound serves as a valuable intermediate for constructing more elaborate molecules. Its fluorinated phenylboronic acid moiety can be incorporated into diverse molecular frameworks for medicinal chemistry and materials development.
Materials Science Research
Due to its electron-deficient tetrafluorophenyl ring, this boronic acid derivative can be utilized in the design and synthesis of novel organic electronic materials, such as those for OLEDs or organic semiconductors.
Pharmaceutical Intermediate
It acts as a building block in the synthesis of pharmacologically active compounds. The introduction of the fluorinated aromatic system can modulate the metabolic stability and binding affinity of drug candidates.
| Molecular weight | 266.00 |
|---|---|
| Empirical formula | C10H11BF4O3 |
| Melting point | 126-133 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Butoxy-2,3,5,6-tetrafluorophenylboronic acid used for?
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This compound is primarily used as a reagent and intermediate in organic synthesis, particularly in Suzuki-Miyaura coupling reactions for creating carbon-carbon bonds. It is also valuable in materials science and pharmaceutical research for synthesizing complex molecules with fluorinated aryl moieties.
What is the CAS number and molecular formula?
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The CAS number for 4-Butoxy-2,3,5,6-tetrafluorophenylboronic acid is 871126-19-1, and its molecular formula is C10H11BF4O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific assay and grade are detailed on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Butoxy-2,3,5,6-tetrafluorophenylboronic acid be handled?
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This compound is a Warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It may also cause long-lasting harmful effects to aquatic life (H413). Handle with appropriate personal protective equipment including a dust mask (type N95), eyeshields, and gloves in a well-ventilated area. Avoid breathing dust. Ensure adequate ventilation, especially if handling large quantities.
Is this chemical available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Butoxy-2,3,5,6-tetrafluorophenylboronic acid, to researchers and institutions worldwide.
How can I request a sample or quote?
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To request a sample or a quotation for 4-Butoxy-2,3,5,6-tetrafluorophenylboronic acid, please contact our sales department through the website or by phone, providing your details and the quantity required.
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