4-[(Trimethylsilyl)ethynyl]benzoic acid
4-\[(Trimethylsilyl)ethynyl\]benzoic acid (CAS: 16116-80-6), with the molecular formula C12H14O2Si and a molecular weight of 218.32 g/mol, is a functionalized alkyne and carboxylic acid derivative. This organic building block features a trimethylsilyl-protected alkyne and a benzoic acid moiety. It serves as a valuable intermediate in organic synthesis, particularly for constructing complex molecules in pharmaceutical research and materials science.
- IUPAC
- (4-Carboxyphenylethynyl)trimethylsilane
- Synonyms
- (4-Carboxyphenylethynyl)trimethylsilane
![4-[(Trimethylsilyl)ethynyl]benzoic acid (C12H14O2Si) — chemical structure, CAS 16116-80-6; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F16116-80-6.png&w=3840&q=75)
Organic Synthesis Intermediate
Serves as a versatile building block in multi-step organic syntheses, enabling the introduction of both an alkyne and a carboxylic acid functionality into target molecules. Its protected alkyne allows for selective downstream reactions.
Pharmaceutical Research
Utilised in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs). The structural motifs present in this compound are relevant for developing molecules with potential therapeutic properties.
Materials Science
Can be employed in the development of advanced materials, such as polymers and functionalised surfaces, where the alkyne and carboxylic acid groups can be used for cross-linking or further modification.
| Molecular weight | 218.32 |
|---|---|
| Empirical formula | C12H14O2Si |
| Storage temperature | 2-8°C |
| Melting point | 154-158 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-\[(Trimethylsilyl)ethynyl\]benzoic acid used for?
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This compound is primarily used as a versatile building block and intermediate in organic synthesis, particularly in pharmaceutical research and materials science for constructing complex molecules.
What are the CAS number and formula for 4-\[(Trimethylsilyl)ethynyl\]benzoic acid?
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The CAS number is 16116-80-6, and the empirical formula is C12H14O2Si.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a research-grade material. The specific purity and assay are detailed in the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for this chemical?
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According to the provided data, this compound is classified with a WGK Germany rating of 3, indicating it is hazardous to water. Appropriate safety precautions should be taken during handling, including wearing protective equipment and avoiding release into the environment.
How is 4-\[(Trimethylsilyl)ethynyl\]benzoic acid typically stored and shipped?
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The recommended storage temperature is 2-8°C. This compound is available for export globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical products.
How can I request a sample or a quote for 4-\[(Trimethylsilyl)ethynyl\]benzoic acid?
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You can request a sample or a quote by contacting our sales team directly through our website or by calling our customer service number. Please specify the CAS number 16116-80-6.
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