4-[(tert-Butyldimethylsilyl)oxy]benzaldehyde
4-[(tert-Butyldimethylsilyl)oxy]benzaldehyde (CAS: 120743-99-9) is an organic compound with the linear formula (CH3)3CSi(CH3)2OC6H4CHO and a molecular weight of 236.38 g/mol. This aldehyde, protected with a tert-butyldimethylsilyl group, serves as a valuable building block in organic synthesis, particularly in the creation of more complex molecules and pharmaceutical intermediates. Its structure facilitates specific chemical transformations.
![4-[(tert-Butyldimethylsilyl)oxy]benzaldehyde ((CH3)3CSi(CH3)2OC6H4CHO) — chemical structure, CAS 120743-99-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F120743-99-9.png&w=3840&q=75)
Organic Synthesis Intermediate
This compound is widely utilised as a versatile intermediate in various organic synthesis pathways. It provides a protected benzaldehyde moiety for controlled reactions, enabling the construction of intricate molecular architectures.
Pharmaceutical Precursor
The protected aldehyde functionality makes it a useful precursor in the synthesis of active pharmaceutical ingredients (APIs) and related drug discovery programs. It allows for sequential modifications of complex organic molecules.
Building Block for Specialty Chemicals
As an organic building block, it is employed in the development of specialty chemicals, fine chemicals, and advanced materials. Its unique structure allows for targeted chemical modifications.
| Molecular weight | 236.38 |
|---|---|
| Linear formula | (CH3)3CSi(CH3)2OC6H4CHO |
| Assay | 97% |
| Boiling point | 224-226 °C(lit.) |
| Density | 0.957 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5110(lit.) |

Hazard statements
- H318Causes serious eye damage
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 41 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-[(tert-Butyldimethylsilyl)oxy]benzaldehyde used for?
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4-[(tert-Butyldimethylsilyl)oxy]benzaldehyde is primarily used as a versatile intermediate and building block in organic synthesis, particularly for the development of pharmaceutical intermediates and specialty chemicals.
What is the CAS number and chemical formula for this compound?
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The CAS number is 120743-99-9, and its linear formula is (CH3)3CSi(CH3)2OC6H4CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated. For specific requirements, please contact us.
What are the safety and handling precautions for 4-[(tert-Butyldimethylsilyl)oxy]benzaldehyde?
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This compound carries a 'Danger' signal word with hazards H318 (Causes serious eye damage) and H413 (May cause long lasting harmful effects to aquatic life). Appropriate personal protective equipment includes eyeshields, gloves, and suitable respiratory protection. Always consult the Safety Data Sheet (SDS) before handling.
How is 4-[(tert-Butyldimethylsilyl)oxy]benzaldehyde packed and exported?
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Tech Serve Solutions professionally packs and exports chemicals globally, adhering to all relevant regulations. Specific packaging details will be provided upon inquiry.
How can I request a sample or quote for this chemical?
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To request a sample or a quotation, please visit the product page and use the 'Request Sample' or 'Request Quote' options, or contact our sales team directly.
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