4-Sulfamoylbenzoic acid
4-Sulfamoylbenzoic acid (CAS: 138-41-0), with the molecular formula HO2CC6H4SO2NH2 and a molecular weight of 201.20 g/mol, is a benzoic acid derivative featuring a sulfonamide group. This compound serves as a valuable building block in organic synthesis and is recognised for its utility in chemical biology and cell biology research. Its bifunctional nature makes it a useful linker in various chemical applications. Tech Serve Solutions supplies this chemical for research and development purposes.
- IUPAC
- 4-Carboxybenzenesulfonamide,Benzoic acid 4-sulfamide

Organic Synthesis Building Block
4-Sulfamoylbenzoic acid is employed as a foundational component in the synthesis of more complex organic molecules. Its carboxylic acid and sulfonamide functionalities allow for diverse chemical modifications and coupling reactions.
Chemical Biology Research
This compound is utilised in chemical biology studies, potentially as a probe or as a precursor to bioactive molecules. Its structure may be incorporated into larger molecules designed to interact with biological systems.
Bioconjugation and Linker Applications
Due to its distinct functional groups, 4-Sulfamoylbenzoic acid can act as a linker or crosslinker in bioconjugation strategies. This enables the covalent attachment of different molecular entities for research purposes.
| Molecular weight | 201.20 |
|---|---|
| Linear formula | HO2CC6H4SO2NH2 |
| Assay | 97% |
| Melting point | 285-295 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CA1(759), CA2(760), CA5A(763), CA5B(11238), CA9(768) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Sulfamoylbenzoic acid used for?
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4-Sulfamoylbenzoic acid is primarily used as a building block in organic synthesis, in chemical biology and cell biology research, and for applications involving linkers and crosslinkers.
What are the CAS number and formula for 4-Sulfamoylbenzoic acid?
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The CAS number is 138-41-0 and the molecular formula is HO2CC6H4SO2NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Sulfamoylbenzoic acid with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 4-Sulfamoylbenzoic acid be handled safely?
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Handling 4-Sulfamoylbenzoic acid requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a WGK rating of 3 in Germany, indicating a high hazard level.
Is 4-Sulfamoylbenzoic acid a controlled substance?
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The provided data does not indicate that 4-Sulfamoylbenzoic acid is a controlled substance.
How is 4-Sulfamoylbenzoic acid packed and exported?
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4-Sulfamoylbenzoic acid is carefully packed for shipping and export, adhering to all relevant regulations for chemical transport. Please contact us for specific export details.
How can I request a sample or quote for 4-Sulfamoylbenzoic acid?
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To request a sample or quote for 4-Sulfamoylbenzoic acid, please use the contact form on our website or contact our sales department directly.
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