4-Pyridylacetonitrile hydrochloride
4-Pyridylacetonitrile hydrochloride (CAS 92333-25-0), with the chemical formula C7H6N2 · HCl and a molecular weight of 154.60 g/mol, is a pyridine derivative. This compound serves as a valuable building block in organic synthesis, particularly for the preparation of complex heterocyclic compounds. Its primary known application is in the synthesis of acrylonitrile derivatives, contributing to the development of novel chemical entities in research and development settings.
- IUPAC
- 4-Pyridineacetonitrile hydrochloride

Intermediate in Organic Synthesis
4-Pyridylacetonitrile hydrochloride is utilised as a key intermediate in the synthesis of various organic compounds. Its structure facilitates the introduction of the pyridylacetonitrile moiety into larger molecular frameworks.
Preparation of Acrylonitrile Derivatives
This compound has been documented for use in the preparation of specific acrylonitrile derivatives, such as (2Z)-3-(4-hydroxyphenyl)-4-pyridin-4-ylacrylonitrile, highlighting its role in specialised chemical research.
Heterocyclic Chemistry Building Block
As a pyridine-based heterocyclic building block, it is instrumental in constructing complex molecular architectures found in medicinal chemistry and material science research.
| Molecular weight | 154.60 |
|---|---|
| Empirical formula | C7H6N2 · HCl |
| Assay | 98% |
| Application | 4-Pyridylacetonitrile hydrochloride was used in preparation of (2Z)-3-(4-hydroxyphenyl)-4-pyridin-4-ylacrylonitrile.1 |
| Melting point | 267 °C (dec.)(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Pyridylacetonitrile hydrochloride used for?
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4-Pyridylacetonitrile hydrochloride is primarily used as a building block in organic synthesis, including the preparation of specific acrylonitrile derivatives and complex heterocyclic compounds.
What are the CAS number and formula for 4-Pyridylacetonitrile hydrochloride?
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The CAS number for 4-Pyridylacetonitrile hydrochloride is 92333-25-0, and its formula is C7H6N2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Pyridylacetonitrile hydrochloride with an assay of 98%. This product is not represented as USP, BP, EP, or any pharmacopoeia grade.
What are the safety considerations when handling 4-Pyridylacetonitrile hydrochloride?
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Warning: 4-Pyridylacetonitrile hydrochloride is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation. Use a dust mask type N95, safety eyeshields, and gloves. Ensure adequate ventilation. Store in a well-ventilated place. Keep container tightly closed.
How is 4-Pyridylacetonitrile hydrochloride packed, shipped, and exported?
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Tech Serve Solutions can export 4-Pyridylacetonitrile hydrochloride globally, adhering to all necessary shipping and handling regulations for chemical products.
How can I request a sample or quote for 4-Pyridylacetonitrile hydrochloride?
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To request a sample or quote, please contact the Tech Serve Solutions sales team through our website or direct contact details.
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