4-Nitrobenzoic hydrazide

CAS 636-97-5O2NC6H4CONHNH2Chemical Synthesis

4-Nitrobenzoic hydrazide (CAS 636-97-5), with the molecular formula O₂NC₆H₄CONHNH₂, is a chemical compound notable for its applications in analytical chemistry and organic synthesis. It serves as a valuable building block in various chemical processes. This compound is supplied by Tech Serve Solutions with a purity of 98%, suitable for research and development purposes.

Email us

4-Nitrobenzoic hydrazide (O2NC6H4CONHNH2) — chemical structure, CAS 636-97-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksCarbonyl CompoundsChemical SynthesisHydrazidesOrganic Building Blocks

01 /Applications

Analytical Standard

4-Nitrobenzoic hydrazide has been utilized as an internal standard in the quantitative determination of isoniazid in human plasma using LC-MS/MS methodology. This application highlights its role in reliable analytical testing.

Organic Synthesis Intermediate

As a derivative of benzoic acid and a hydrazide, this compound functions as a versatile intermediate in organic synthesis. Its structure allows for further chemical modifications to create more complex molecules.

Research and Development

This compound is employed in research laboratories for exploring new synthetic pathways and developing novel chemical entities. Its availability as a building block supports innovation in chemical sciences.

02 /Properties

Molecular weight	181.15
Linear formula	O2NC6H4CONHNH2
Assay	98%
Solubility	acetone: soluble0.5 g/10 mL, clear, yellow
Application	4-Nitrobenzoic hydrazide has been used as internal standard in determination of isoniazid in human plasma by LC-MS/MS method1.
Melting point	218 °C (dec.)(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-37/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

636-97-5

MDL number

MFCD00007604

PubChem substance

24855425

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Nitrobenzoic hydrazide primarily used for?

4-Nitrobenzoic hydrazide is primarily used as an internal standard in analytical methods, such as the determination of isoniazid in plasma, and as a building block in organic synthesis.

What is the CAS number and molecular formula for 4-Nitrobenzoic hydrazide?

The CAS number is 636-97-5 and the molecular formula is O₂NC₆H₄CONHNH₂.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 4-Nitrobenzoic hydrazide with an assay of 98%. We do not represent this product as USP, BP, or EP grade.

How should 4-Nitrobenzoic hydrazide be handled safely?

Due to its potential to cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335), appropriate personal protective equipment including a dust mask (N95), eyeshields, and gloves should be used. Handle in a well-ventilated area.