4′-Methylbiphenyl-4-sulfonyl chloride
4′-Methylbiphenyl-4-sulfonyl chloride (CAS: 101366-51-2) is a chemical compound with the formula C13H11ClO2S and a molecular weight of 266.74 g/mol. As a sulfonyl halide, it serves as a valuable building block in organic synthesis. Its reactivity makes it useful for introducing the 4′-methylbiphenyl-4-sulfonyl group into various molecules, facilitating the creation of complex chemical structures.
- IUPAC
- 4-(p-Tolyl)benzenesulfonyl chloride,4-(4-Methylphenyl)benzenesulfonyl chloride
- Synonyms
- 4-(p-Tolyl)benzenesulfonyl chloride4-(4-Methylphenyl)benzenesulfonyl chloride

Organic Synthesis Intermediate
This compound functions as a key intermediate in the synthesis of diverse organic molecules. It is employed to create new carbon-sulfur bonds, essential for constructing more complex chemical architectures.
Pharmaceutical Research
In pharmaceutical research, 4′-Methylbiphenyl-4-sulfonyl chloride can be utilised in the development of novel drug candidates. Its structural features may be incorporated into biologically active compounds.
Material Science
The compound may find applications in material science for modifying polymers or creating novel functional materials. Its sulfonyl chloride group allows for derivatisation and integration into larger molecular frameworks.
| Molecular weight | 266.74 |
|---|---|
| Empirical formula | C13H11ClO2S |
| Assay | 95% |
| Melting point | 105-110 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 3261 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Methylbiphenyl-4-sulfonyl chloride used for?
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4′-Methylbiphenyl-4-sulfonyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly for introducing the 4′-methylbiphenyl-4-sulfonyl moiety into other molecules.
What is the CAS number and chemical formula for 4′-Methylbiphenyl-4-sulfonyl chloride?
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The CAS number is 101366-51-2, and its chemical formula is C13H11ClO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-Methylbiphenyl-4-sulfonyl chloride with an assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 4′-Methylbiphenyl-4-sulfonyl chloride be handled?
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This compound is classified as Danger and causes severe skin burns and eye damage (H314). It reacts violently with water. Handle with appropriate personal protective equipment (gloves, eye protection) in a well-ventilated area. Avoid contact with water. Refer to the Safety Data Sheet for detailed handling instructions.
Is this product shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents, including 4′-Methylbiphenyl-4-sulfonyl chloride.
How can I request a quote or sample?
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To request a quote or sample of 4′-Methylbiphenyl-4-sulfonyl chloride, please contact our sales team through the website or by phone.
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