4′-Methylacetanilide
4′-Methylacetanilide (CAS: 103-89-9) is an organic compound with the linear formula CH₃CONHC₆H₄CH₃ and a molecular weight of 149.19 g/mol. This white crystalline solid is primarily utilised as a building block in chemical synthesis. Its properties make it a useful intermediate for the preparation of more complex organic molecules, particularly within nitrogen compound chemistry and as a protected amine.
- IUPAC
- p-Acetotoluidide
- Synonyms
- p-AcetotoluidideN-Acetyl-p-toluidine4-Acetamidotoluene

Synthesis of Phosphorus Ylides
4′-Methylacetanilide has been documented for its use in the synthesis of stable crystalline phosphorus ylides. This application highlights its role as a reactant in advanced organic synthesis pathways.
Organic Synthesis Intermediate
As a protected amine and nitrogen compound, 4′-Methylacetanilide serves as a versatile intermediate in multi-step organic syntheses. It enables the introduction of specific structural motifs into target molecules.
Research and Development
This compound is employed in research laboratories for exploring new chemical reactions and developing novel organic compounds. Its well-defined structure facilitates predictable reactivity in synthetic strategies.
| Molecular weight | 149.19 |
|---|---|
| Linear formula | CH3CONHC6H4CH3 |
| Assay | 99% |
| Boiling point | 307 °C(lit.) |
| Application | 4′-Methylacetanilide was used in the synthesis of stable crystalline phosphorus ylides1. |
| Melting point | 149-151 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4′-Methylacetanilide used for?
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4′-Methylacetanilide is used as a building block in chemical synthesis, notably in the preparation of stable crystalline phosphorus ylides. It also functions as an intermediate in organic synthesis and is utilized in research and development.
What are the CAS number and chemical formula for 4′-Methylacetanilide?
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The CAS number for 4′-Methylacetanilide is 103-89-9. Its linear chemical formula is CH₃CONHC₆H₄CH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4′-Methylacetanilide with a purity of 99%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should 4′-Methylacetanilide be handled safely?
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4′-Methylacetanilide is a warning substance that can cause gastrointestinal irritation if swallowed (H302), and skin (H315), eye (H319), and respiratory tract irritation (H335). It is recommended to wear a dust mask type N95 (US), eyeshields, and gloves, and to avoid breathing dust. Ensure adequate ventilation.
Is 4′-Methylacetanilide a controlled substance?
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The provided data does not indicate that 4′-Methylacetanilide is a controlled substance.
How is 4′-Methylacetanilide packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports chemicals globally, adhering to all necessary regulations for safe transit.
How can I request a sample or quote for 4′-Methylacetanilide?
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To request a sample or a quote for 4′-Methylacetanilide, please contact the TSS sales team via our website or direct contact information.
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