4-Methoxytriphenylmethyl chloride
4-Methoxytriphenylmethyl chloride (CAS 14470-28-1), with the molecular formula C20H17ClO, is a valuable chemical reagent with a molecular weight of 308.80 g/mol. It serves as a selective protecting agent, primarily utilised for the protection of primary hydroxyl groups in organic synthesis. Its specific reactivity makes it a useful tool in multi-step synthetic procedures, particularly in the pharmaceutical and fine chemical industries.
- IUPAC
- 4-Methoxytriphenylchloromethane,4-Methoxytrityl chloride,p-Anisylchlorodiphenylmethane,p-Monomethoxytrityl chloride,MMT
- Synonyms
- 4-Methoxytriphenylchloromethane4-Methoxytrityl chloridep-Anisylchlorodiphenylmethanep-Monomethoxytrityl chlorideMMT
Selective Protection of Hydroxyl Groups
4-Methoxytriphenylmethyl chloride is employed as a reagent for the selective protection of primary hydroxyl groups. This protection strategy is crucial in complex organic syntheses where precise control over reaction pathways is required.
Organic Synthesis
As a versatile synthetic reagent, it finds application in various multi-step organic transformations. Its ability to selectively block functional groups allows for controlled manipulation of molecules, aiding in the construction of complex organic architectures.
Protecting Group Chemistry
This compound is a key player in the field of protecting group chemistry. Its introduction and subsequent removal enable chemists to carry out reactions on other parts of a molecule without affecting sensitive hydroxyl functionalities.
| Molecular weight | 308.80 |
|---|---|
| Linear formula | CH3OC6H4C(C6H5)2Cl |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Application | Selective protecting reagent for primary hydroxyl groups.1,2 |
| Melting point | 122-124 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methoxytriphenylmethyl chloride primarily used for?
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It is primarily used as a selective protecting reagent for primary hydroxyl groups in organic synthesis.
What is the CAS number and chemical formula for 4-Methoxytriphenylmethyl chloride?
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The CAS number is 14470-28-1 and the chemical formula is C20H17ClO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methoxytriphenylmethyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for 4-Methoxytriphenylmethyl chloride?
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This compound is a warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95 US type), eyeshields, and gloves, should be worn. Ensure adequate ventilation.
How is 4-Methoxytriphenylmethyl chloride stored and shipped?
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It is recommended to store 4-Methoxytriphenylmethyl chloride at 2-8°C. TSS can export this chemical globally.
How can I request a quote or sample for 4-Methoxytriphenylmethyl chloride?
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Please contact the TSS sales team via our website or direct inquiry for quotes or sample requests.
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