4-Methoxyisophthalonitrile
4-Methoxyisophthalonitrile (CAS: 80323-72-4), with the molecular formula CH3OC6H3(CN)2 and a molecular weight of 158.16 g/mol, is a valuable organic building block. This chemical compound serves as a key intermediate in various synthesis pathways. Its structure, featuring methoxy and dinitrile functional groups on a benzene ring, makes it suitable for further chemical modifications and incorporation into more complex molecular architectures within research and industrial applications.
- IUPAC
- (2,4-dicyanomethoxybenzene)

Chemical Synthesis Intermediate
4-Methoxyisophthalonitrile is employed as a fundamental building block in organic synthesis. Its reactive nitrile groups and aromatic structure allow for diverse chemical transformations, facilitating the creation of novel compounds for research and development.
Development of Specialty Chemicals
This compound serves as a precursor in the synthesis of specialty chemicals, contributing to the development of new materials and fine chemical products across various industries.
Research and Development
Researchers utilise 4-Methoxyisophthalonitrile in academic and industrial laboratories for exploring new chemical reactions and developing innovative molecular structures.
| Molecular weight | 158.16 |
|---|---|
| Linear formula | CH3OC6H3(CN)2 |
| Assay | 97% |
| Melting point | 205-209 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 22-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methoxyisophthalonitrile used for?
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4-Methoxyisophthalonitrile is used as a building block in chemical synthesis and for the development of specialty chemicals and in research and development activities.
What is the CAS number and formula for 4-Methoxyisophthalonitrile?
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The CAS number for 4-Methoxyisophthalonitrile is 80323-72-4, and its molecular formula is CH3OC6H3(CN)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methoxyisophthalonitrile with an assay of 97%. This product is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the primary hazards associated with 4-Methoxyisophthalonitrile?
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4-Methoxyisophthalonitrile is classified with the GHS07 symbol and a 'Warning' signal word. It carries hazard statements H302 (Harmful if swallowed), H312 (Harmful in contact with skin), and H332 (Harmful if inhaled). Appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves, should be used when handling this chemical.
How is 4-Methoxyisophthalonitrile packed, shipped, and exported?
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Tech Serve Solutions, a global supplier and exporter, ensures that 4-Methoxyisophthalonitrile is packed and shipped in compliance with international regulations for chemical transport.
How can I request a quote or sample?
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To request a quote or a sample of 4-Methoxyisophthalonitrile, please contact the Tech Serve Solutions sales team through our official channels.
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