4-Isoquinolineboronic acid pinacol ester
4-Isoquinolineboronic acid pinacol ester (CAS: 685103-98-4; Formula: C15H18BNO2; MW: 255.12) is a heterocyclic boronate ester utilised in organic synthesis. It serves as a valuable building block in the construction of complex molecules, particularly in cross-coupling reactions. Its structure, featuring the isoquinoline core and a pinacol boronate ester moiety, makes it suitable for introducing the isoquinoline fragment into various organic frameworks.
- IUPAC
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinoline
Suzuki-Miyaura Cross-Coupling Reactions
This compound is a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds. It is used to introduce the 4-isoquinolyl group onto aryl or vinyl halides and pseudohalides.
Organic Synthesis Building Block
As a versatile building block, it facilitates the synthesis of diverse isoquinoline derivatives. These derivatives can be explored for their potential applications in medicinal chemistry and materials science.
Medicinal Chemistry Research
The isoquinoline scaffold is prevalent in many biologically active compounds. This boronate ester provides a convenient method for synthesising novel isoquinoline-containing molecules for pharmaceutical research.
| Molecular weight | 255.12 |
|---|---|
| Empirical formula | C15H18BNO2 |
| Assay | 96% |
| Melting point | 98-102 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Isoquinolineboronic acid pinacol ester used for?
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4-Isoquinolineboronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions to introduce the 4-isoquinolyl moiety into target molecules.
What are the CAS number and formula for 4-Isoquinolineboronic acid pinacol ester?
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The CAS number is 685103-98-4, and the empirical formula (Hill notation) is C15H18BNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Isoquinolineboronic acid pinacol ester with an assay of 96%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 4-Isoquinolineboronic acid pinacol ester be handled?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. This compound may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Is 4-Isoquinolineboronic acid pinacol ester a controlled substance?
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The provided data does not indicate that 4-Isoquinolineboronic acid pinacol ester is a controlled substance.
How is this chemical exported and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Products are carefully packaged and shipped according to international regulations.
How can I request a quote or sample?
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Please contact Tech Serve Solutions directly through our website or by phone to request a quote or sample of 4-Isoquinolineboronic acid pinacol ester.
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