4-Hydroxy-6-(trifluoromethyl)pyrimidine
4-Hydroxy-6-(trifluoromethyl)pyrimidine (CAS: 1546-78-7) is a trifluoromethyl-substituted pyrimidine derivative with the molecular formula C5H3F3N2O and a molecular weight of 164.09 g/mol. This heterocyclic compound serves as a valuable building block in chemical synthesis, particularly for the creation of novel organic molecules and complex chemical structures. Its specific structural features make it a useful intermediate in research and development across various scientific disciplines.
- IUPAC
- 6-(Trifluoromethyl)-4-pyrimidinol
- Synonyms
- 6-(Trifluoromethyl)-4-pyrimidinol

Chemical Synthesis Intermediate
Utilised as a versatile building block in organic synthesis. It facilitates the construction of more complex molecules due to the presence of the pyrimidine ring and the trifluoromethyl group.
Pharmaceutical Research
Serves as a precursor in the development of potential pharmaceutical agents. Its structure may be incorporated into drug candidates targeting various therapeutic areas.
Agrochemical Development
A key component in the synthesis of new agrochemicals. The trifluoromethyl moiety can impart desirable properties like enhanced stability and biological activity.
Materials Science
Investigated for its potential use in the creation of advanced materials. Its unique electronic and structural properties could be exploited in specialised applications.
| Molecular weight | 164.09 |
|---|---|
| Empirical formula | C5H3F3N2O |
| Assay | 99% |
| Melting point | 169-171 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxy-6-(trifluoromethyl)pyrimidine used for?
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4-Hydroxy-6-(trifluoromethyl)pyrimidine is primarily used as a building block in chemical synthesis, including pharmaceutical research, agrochemical development, and materials science.
What is the CAS number and chemical formula for this compound?
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The CAS number is 1546-78-7 and the chemical formula is C5H3F3N2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Hydroxy-6-(trifluoromethyl)pyrimidine with an assay of 99%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should 4-Hydroxy-6-(trifluoromethyl)pyrimidine be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust. In case of contact with eyes, rinse cautiously with water for several minutes. Ensure adequate ventilation.
Is this chemical a controlled substance?
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Based on the provided data, there is no indication that 4-Hydroxy-6-(trifluoromethyl)pyrimidine is a controlled substance.
How is this product packed and shipped?
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4-Hydroxy-6-(trifluoromethyl)pyrimidine is carefully packed for stable transport and is available for global export by Tech Serve Solutions.
How can I request a sample or quote?
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To request a sample or a quote for 4-Hydroxy-6-(trifluoromethyl)pyrimidine, please contact the Tech Serve Solutions sales team through our website or listed contact details.
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