4-Hydroxy-2-methyl-8-trifluoromethylquinoline
4-Hydroxy-2-methyl-8-trifluoromethylquinoline (CAS 140908-88-9) is a fluorinated heterocyclic compound with the molecular formula C11H8F3NO and a molecular weight of 227.18 g/mol. This chemical serves as a versatile building block in organic synthesis, particularly for creating complex molecules incorporating a quinoline core and a trifluoromethyl group. Its structure lends itself to applications in materials science and pharmaceutical research as an intermediate for novel compounds.

Organic Synthesis Intermediate
This quinoline derivative is a valuable intermediate for the synthesis of more complex organic molecules. Its trifluoromethyl and hydroxyl functionalities offer reactive sites for further chemical transformations.
Fluorinated Building Block
As a fluorinated heterocycle, it is employed in the construction of novel compounds where the introduction of fluorine atoms is desired to modify properties such as lipophilicity and metabolic stability.
Research and Development
Utilised in academic and industrial research laboratories for the exploration of new chemical entities with potential applications in various fields, including medicinal chemistry and materials science.
| Molecular weight | 227.18 |
|---|---|
| Empirical formula | C11H8F3NO |


Hazard statements
- H301Toxic if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-41 |
| Safety statements (S) | 26-39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Hydroxy-2-methyl-8-trifluoromethylquinoline used for?
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4-Hydroxy-2-methyl-8-trifluoromethylquinoline is primarily used as a building block in organic synthesis and in research and development for creating complex fluorinated heterocyclic compounds.
What are the CAS number and chemical formula?
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The CAS number is 140908-88-9, and the empirical formula is C11H8F3NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and chemical synthesis purposes. The specific assay and purity are detailed in the product specifications; it is not supplied as USP, BP, or EP grade.
How should 4-Hydroxy-2-methyl-8-trifluoromethylquinoline be handled?
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This compound is classified as dangerous. It is harmful if swallowed and causes serious eye damage. Handle with appropriate personal protective equipment, including eye protection and protective gloves. Avoid ingestion and contact with eyes. Refer to the Safety Data Sheet for comprehensive handling information. It is labelled with GHS05 and GHS06 symbols, with the signal word 'Danger'.
Is this product regulated or a controlled substance?
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The provided data does not indicate that this compound is a controlled substance. However, users should always verify local regulations.
How is this chemical packed and shipped?
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Tech Serve Solutions exports this chemical globally, adhering to all necessary transport regulations for hazardous materials, including UN 2811 6.1 / PGIII classification.
How can I request a sample or quote?
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To request a sample or obtain a quote for 4-Hydroxy-2-methyl-8-trifluoromethylquinoline, please contact the Tech Serve Solutions sales department through our website or by phone.
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