4-Cyano-2-fluoropyridine
4-Cyano-2-fluoropyridine (CAS: 3939-14-8; C6H3FN2) is a valuable fluorinated pyridine building block with a molecular weight of 122.10 g/mol. This compound is essential in organic synthesis, particularly for the introduction of fluorinated pyridine moieties into complex molecules. It serves as a key intermediate in the development of pharmaceuticals, agrochemicals, and materials science applications, owing to the unique electronic and steric properties conferred by the fluorine atom and cyano group.

Pharmaceutical Intermediate
4-Cyano-2-fluoropyridine is utilized as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its fluorinated pyridine structure is incorporated into drug candidates to modulate pharmacokinetic properties such as metabolic stability and bioavailability.
Agrochemical Synthesis
This compound serves as a precursor in the development of novel agrochemicals, including herbicides, insecticides, and fungicides. The presence of fluorine can enhance the efficacy and environmental profile of these agricultural products.
Materials Science
4-Cyano-2-fluoropyridine can be employed in the synthesis of advanced materials. Its unique structure may contribute to the development of functional polymers, liquid crystals, or organic electronic components.
Organic Synthesis Reagent
As a versatile building block, it enables chemists to construct complex heterocyclic compounds. The reactive cyano and fluoro groups allow for diverse derivatization pathways in research and development settings.
| Molecular weight | 122.10 |
|---|---|
| Empirical formula | C6H3FN2 |
| Assay | 97% |
| Melting point | 29-34 °C |


Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H318Causes serious eye damage
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 82 °C / 179.6 °F |
| Transport (UN / ADR) | UN 3439 6.1 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-37/38-41 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Cyano-2-fluoropyridine used for?
+
4-Cyano-2-fluoropyridine is primarily used as a building block in organic synthesis for the development of pharmaceuticals, agrochemicals, and advanced materials. Its fluorinated pyridine structure is valuable for introducing specific electronic and steric properties into target molecules.
What is the CAS number and formula for 4-Cyano-2-fluoropyridine?
+
The CAS number for 4-Cyano-2-fluoropyridine is 3939-14-8, and its empirical formula is C6H3FN2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Cyano-2-fluoropyridine with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 4-Cyano-2-fluoropyridine be handled?
+
4-Cyano-2-fluoropyridine is classified as a Danger substance. It is harmful if swallowed, in contact with skin, or if inhaled, causes skin irritation, serious eye damage, and respiratory irritation. Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Handle in a well-ventilated area and avoid dust formation.
Is 4-Cyano-2-fluoropyridine shipped internationally?
+
Yes, Tech Serve Solutions exports a wide range of chemicals globally, including 4-Cyano-2-fluoropyridine, adhering to all international shipping regulations.
How can I request a quote or sample?
+
To request a quote or a sample of 4-Cyano-2-fluoropyridine, please contact our sales department through the website or by phone, providing your specific requirements.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis