4-Chlorobutyryl chloride
4-Chlorobutyryl chloride (CAS 4635-59-0) is a reactive organic compound with the linear formula Cl(CH2)3COCl and a molecular weight of 141.00 g/mol. It serves as a key intermediate and building block in various organic syntheses. Its acyl chloride functionality allows it to participate in numerous reactions, making it valuable for the preparation of complex molecules in the pharmaceutical and chemical industries. Tech Serve Solutions supplies this chemical with a high purity assay.

Pharmaceutical Intermediate
4-Chlorobutyryl chloride is utilised in the synthesis of active pharmaceutical ingredients (APIs). Its structure allows for the introduction of a four-carbon chain with a reactive end group, facilitating the construction of complex drug molecules.
Organic Synthesis Building Block
As a versatile building block, this compound is employed in a wide range of organic transformations. It is particularly useful for introducing the 4-chlorobutyryl moiety into various substrates via acylation reactions.
Agrochemical Synthesis
The reactivity of 4-Chlorobutyryl chloride makes it a useful intermediate in the production of certain agrochemicals. It can be incorporated into molecules designed for crop protection and pest management.
Material Science
This acid halide can be used in the development of novel polymers and materials. Its ability to react with nucleophiles allows for its incorporation into polymer backbones or as a modifying agent.
| Molecular weight | 141.00 |
|---|---|
| Linear formula | Cl(CH2)3COCl |
| Assay | 99% |
| Boiling point | 173-174 °C(lit.) |
| Density | 1.26 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.461(lit.) |
| Vapour pressure | 3 mmHg (20 °C) |
| Autoignition temp | 824 °F |


Hazard statements
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 85 °C / 185 °F |
| Transport (UN / ADR) | UN 3390 8(6.1) / PGI |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 22-23-35 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chlorobutyryl chloride used for?
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4-Chlorobutyryl chloride is primarily used as an intermediate and building block in organic synthesis, particularly in the pharmaceutical and agrochemical industries, for the preparation of complex molecules.
What is the CAS number and chemical formula for 4-Chlorobutyryl chloride?
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The CAS number is 4635-59-0 and the linear chemical formula is Cl(CH2)3COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chlorobutyryl chloride with an assay of 99%. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should 4-Chlorobutyryl chloride be handled safely?
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4-Chlorobutyryl chloride is a corrosive and toxic substance (H302-H314-H330). Handle with extreme care using appropriate personal protective equipment including gloves, goggles, face shields, and a suitable respirator. Ensure good ventilation and avoid contact with skin, eyes, and inhalation.
Is 4-Chlorobutyryl chloride a controlled substance?
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The provided data does not indicate that 4-Chlorobutyryl chloride is a controlled substance.
How is 4-Chlorobutyryl chloride packed, shipped, and exported?
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4-Chlorobutyryl chloride is shipped as UN 3390, Hazard Class 8(6.1), Packing Group I, in compliance with transportation regulations. Tech Serve Solutions exports fine chemicals globally.
How can I request a quote or sample for 4-Chlorobutyryl chloride?
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To request a quote or sample, please contact our sales department through the website or by phone, providing your details and the product CAS number (4635-59-0).
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