4-Chlorobenzonitrile
4-Chlorobenzonitrile (CAS: 623-03-0, Formula: ClC6H4CN, Molar Mass: 137.57) is a versatile organic compound categorised as a building block. It features a nitrile group and a chlorine atom attached to a benzene ring, making it a valuable intermediate in organic synthesis. This chemical is primarily used in the preparation of amides and other derivatives within chemical manufacturing and research laboratories. Tech Serve Solutions supplies this compound with a high assay for demanding applications.

Intermediate for Amide Synthesis
4-Chlorobenzonitrile serves as a precursor in the synthesis of various amide compounds. Its reactive nitrile group can be readily hydrolysed or reacted with other reagents to form diverse amide structures, essential in many organic chemistry pathways.
Building Block in Organic Synthesis
As a key building block, this compound facilitates the introduction of the 4-chlorobenzonitrile moiety into more complex molecules. It is utilised in research and development for creating novel compounds with potential applications in materials science and pharmaceuticals.
Reagent in Chemical Research
Researchers employ 4-Chlorobenzonitrile in laboratory settings for synthetic transformations. Its well-defined chemical properties make it a reliable reagent for developing new synthetic methodologies and exploring reaction mechanisms.
| Molecular weight | 137.57 |
|---|---|
| Linear formula | ClC6H4CN |
| Assay | 99% |
| Boiling point | 223 °C(lit.) |
| Application | 4-Chlorobenzonitrile has been used in the preparation of amides1. |
| Melting point | 90-93 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/22-36/37/38 |
| Safety statements (S) | 23-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chlorobenzonitrile used for?
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4-Chlorobenzonitrile is primarily used as a building block in organic synthesis and as an intermediate in the preparation of amides and other chemical derivatives.
What are the CAS number and formula for 4-Chlorobenzonitrile?
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The CAS number for 4-Chlorobenzonitrile is 623-03-0, and its linear formula is ClC6H4CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chlorobenzonitrile with a minimum assay of 99%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and technical applications.
How should 4-Chlorobenzonitrile be handled?
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Handle 4-Chlorobenzonitrile with appropriate personal protective equipment, including a dust mask (N95 recommended), eyeshields, faceshields, and gloves. Avoid breathing dust and ensure adequate ventilation due to its irritant properties (H315, H319, H335) and harmful effects if swallowed or inhaled (H302, H332).
Is 4-Chlorobenzonitrile a controlled substance?
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Based on the provided data, 4-Chlorobenzonitrile is not indicated as a controlled substance.
How is 4-Chlorobenzonitrile shipped and exported?
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Tech Serve Solutions, as a global supplier and exporter, ships and exports chemicals like 4-Chlorobenzonitrile according to international regulations for hazardous materials. Please contact us for specific shipping and export details.
How can I request a sample or quote for 4-Chlorobenzonitrile?
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To request a sample or obtain a quote for 4-Chlorobenzonitrile, please use the 'Contact Us' form or reach out to our sales team directly through the details provided on our website.
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