4-Chlorobenzhydrazide
4-Chlorobenzhydrazide (CAS: 536-40-3) is an organic compound with the molecular formula ClC₆H₄CONHNH₂ and a molecular weight of 170.60 g/mol. It serves as a valuable building block in organic synthesis. This compound is primarily utilised in the preparation of various derivatives, including mesogenic hydrazides and substituted hydrazones, making it an important intermediate for research and development in materials science and medicinal chemistry.
Synthesis of Mesogenic Hydrazide Derivatives
4-Chlorobenzhydrazide is employed in the Schotten-Baumann reaction with 4-n-alkoxybenzoyl chloride to synthesise rod-shaped mesogenic hydrazide derivatives, useful in materials science research.
Preparation of Hydrazone Compounds
The compound is a precursor for various hydrazone derivatives when reacted with substituted benzaldehydes, such as 4-methoxybenzaldehyde, 4-hydroxybenzaldehyde, 2-nitrobenzaldehyde, and benzaldehyde.
Organic Synthesis Intermediate
As a functionalised hydrazide, 4-Chlorobenzhydrazide acts as a versatile intermediate for creating more complex organic molecules in academic and industrial research settings.
| Molecular weight | 170.60 |
|---|---|
| Linear formula | ClC6H4CONHNH2 |
| Assay | 98% |
| Application | 4-Chlorobenzhydrazide has been used in preparation of:• rod-shaped mesogenic hydrazide derivatives via Schotten-Baumann reaction with 4-n-alkoxybenzoyl chloride1• 4-methoxybenzaldehyde-4-chlorophenyl-1-carbonyl hydrazone2• 4-hydroxybenzaldehyde-4-chlorophenyl-1-carbonylhydrazone2• 2-nitrobenzaldehyde-4-chlorophenyl-1-carbonylhydrazone2• benzaldehyde-4-chlorophenyl-1-carbonylhydrazone2 |
| Melting point | 162-165 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chlorobenzhydrazide used for?
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4-Chlorobenzhydrazide is used as a building block in organic synthesis, particularly for preparing rod-shaped mesogenic hydrazide derivatives and various substituted hydrazone compounds.
What are the CAS number and formula for 4-Chlorobenzhydrazide?
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The CAS number for 4-Chlorobenzhydrazide is 536-40-3, and its linear formula is ClC₆H₄CONHNH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chlorobenzhydrazide with a minimum purity of 98%. This product is suitable for research and general laboratory use. We do not represent it as USP, BP, or EP grade.
What are the safety and handling recommendations for 4-Chlorobenzhydrazide?
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4-Chlorobenzhydrazide is classified as a warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It should be handled with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area.
How is 4-Chlorobenzhydrazide packed, shipped, and exported?
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Tech Serve Solutions carefully packs 4-Chlorobenzhydrazide to ensure product integrity during transit. We are experienced in exporting chemicals globally, adhering to all relevant international shipping regulations.
How can I request a quote or sample of 4-Chlorobenzhydrazide?
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To request a quote or a sample of 4-Chlorobenzhydrazide, please contact our sales department through the website or by phone. Our team will be pleased to assist you.
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