4-Chloro-3-(trifluoromethyl)aniline
4-Chloro-3-(trifluoromethyl)aniline (CAS: 320-51-4) is a key organic intermediate with the molecular formula ClC6H3(CF3)NH2 and a molecular weight of 195.57 g/mol. This compound serves as a valuable building block in chemical synthesis, particularly for the development of pharmaceuticals and agrochemicals. Its unique structure, featuring both a trifluoromethyl group and a chlorine atom on the aniline ring, allows for diverse chemical modifications, making it an important reagent for creating complex molecules.
- IUPAC
- 4-Chloro-α,α,α-trifluoro-m-toluidine,5-Amino-2-chlorobenzotrifluoride
- Synonyms
- 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine5-Amino-2-chlorobenzotrifluoride
Pharmaceutical Intermediates
This aniline derivative is frequently employed in the synthesis pathways for active pharmaceutical ingredients (APIs). Its specific functional groups facilitate the construction of complex heterocyclic systems found in various drug candidates.
Agrochemical Development
It acts as a crucial precursor in the production of certain pesticides and herbicides. The trifluoromethyl and chloro substituents can impart desirable properties to the final agrochemical product.
Organic Synthesis Reagent
As a versatile building block, 4-Chloro-3-(trifluoromethyl)aniline is used in a wide range of organic transformations. It enables the introduction of specific structural motifs into target molecules for research and development.
| Molecular weight | 195.57 |
|---|---|
| Linear formula | ClC6H3(CF3)NH2 |
| Assay | 99% |
| Melting point | 35-37 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 22-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-3-(trifluoromethyl)aniline used for?
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4-Chloro-3-(trifluoromethyl)aniline is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, and as a general building block in organic synthesis.
What is the CAS number and chemical formula for 4-Chloro-3-(trifluoromethyl)aniline?
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The CAS number is 320-51-4, and the chemical formula is ClC6H3(CF3)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-3-(trifluoromethyl)aniline with an assay of 99%. This is a technical/research grade, and we do not represent it as USP, BP, or EP.
How should 4-Chloro-3-(trifluoromethyl)aniline be handled safely?
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This compound is harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation.
How is 4-Chloro-3-(trifluoromethyl)aniline packed and shipped?
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Tech Serve Solutions securely packs and exports fine chemicals globally, adhering to all necessary regulations for safe transport.
How can I request a quote or sample?
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To request a quote or sample of 4-Chloro-3-(trifluoromethyl)aniline, please contact our sales team through the website or by phone.
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