4-Chloro-3,5-dinitrobenzotrifluoride
4-Chloro-3,5-dinitrobenzotrifluoride (CAS: 393-75-9) is a trifluoromethylated nitroaromatic compound with the molecular formula C7H2ClF3N2O5 and a molar mass of 270.55 g/mol. This chemical serves as a valuable building block in organic synthesis. Its primary applications include derivatization for analytical purposes, such as in the determination of amikacin and amino acids via HPLC, and as a precursor in the synthesis of various complex organic molecules.
- IUPAC
- CDNT,DNT-Cl
- Synonyms
- ClC6H2(NO2)2CF3
Derivatization Reagent in HPLC Analysis
Utilised as a derivatization reagent for the high-performance liquid chromatography (HPLC) determination of amikacin in water samples and amino acids. This enhances the detectability of these analytes.
Synthesis of N-Aryl Derivatives
Employed in the synthesis of N-(2,6-dinitro-4-trifluoromethylphenyl)aniline derivatives, showcasing its utility in constructing complex aromatic structures.
Precursor for Heterocyclic Compounds
Used in the synthesis of specific heterocyclic compounds, such as 4,6-dinitro-2,8-bis(trifluoromethyl)phenothiazine and related sulfides, contributing to the development of novel chemical entities.
| Molecular weight | 270.55 |
|---|---|
| Linear formula | ClC6H2(NO2)2CF3 |
| Assay | 99% |
| Solubility | water: insoluble |
| Application | 4-Chloro-3,5-dinitrobenzotrifluoride was used:• as derivatization reagent in determination of amikacin in water samples1 and amino acids2 by HPLC• in the synthesis of N-(2,6-dinitro-4-trifluoromethylphenyl)aniline derivatives3• in the synthesis of 4,6-dinitro-2,8-bis(trifluoromethyl)phenothiazine and isopropyl-2,6-dinitro-4-trifluoromethylphenyl sulfide4 |
| Melting point | 50-55 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H310Fatal in contact with skin
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P302IF ON SKIN
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Flash point | 126 °C / 258.8 °F |
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 22-24 |
| Safety statements (S) | 36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-3,5-dinitrobenzotrifluoride used for?
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4-Chloro-3,5-dinitrobenzotrifluoride is used as a derivatization reagent in HPLC analysis for compounds like amikacin and amino acids, and as a building block in the synthesis of various organic molecules, including N-aryl derivatives and heterocyclic compounds.
What is the CAS number and formula for 4-Chloro-3,5-dinitrobenzotrifluoride?
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The CAS number is 393-75-9, and the linear formula is ClC6H2(NO2)2CF3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-3,5-dinitrobenzotrifluoride with an assay of 99%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 4-Chloro-3,5-dinitrobenzotrifluoride be handled safely?
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This compound is classified as toxic if swallowed and toxic in contact with skin (H302, H310). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a P2 respirator cartridge. Ensure adequate ventilation and avoid exposure.
Is 4-Chloro-3,5-dinitrobenzotrifluoride suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Chloro-3,5-dinitrobenzotrifluoride, adhering to all relevant shipping and regulatory requirements.
How can I request a sample or quote for 4-Chloro-3,5-dinitrobenzotrifluoride?
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To request a sample or a quote, please contact our sales team directly through the TSS website or by calling our customer service line.
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