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4-Chloro-3-nitroanisole

CAS 10298-80-3ClC6H3(NO2)OCH3Chemical Synthesis

4-Chloro-3-nitroanisole (CAS: 10298-80-3) is an organic compound with the formula ClC6H3(NO2)OCH3. This chemical, with a molecular weight of 187.58 g/mol, serves as a valuable building block in organic synthesis. Its primary application lies in the preparation of complex molecules, particularly within research and development settings in the chemical and pharmaceutical industries.

IUPAC
1-Chloro-4-methoxy-2-nitrobenzene
Synonyms
1-Chloro-4-methoxy-2-nitrobenzene
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4-Chloro-3-nitroanisole (ClC6H3(NO2)OCH3) — chemical structure, CAS 10298-80-3; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisNitro CompoundsNitrogen CompoundsOrganic Building Blocks
01 /Applications

Synthesis of Chromone Derivatives

4-Chloro-3-nitroanisole is utilised as a precursor in the synthesis of various derivatives of 7-methanesulfonylamino-6-phenoxychromone. It is involved in modifications at both the pyrone and phenoxy rings of the target molecules.

Organic Synthesis Intermediate

As a substituted nitroanisole, it functions as a versatile intermediate in the construction of more complex organic structures. Its reactive chloro and nitro groups allow for diverse chemical transformations.

Research and Development

This compound is employed in laboratory settings for research purposes, enabling the exploration of new chemical pathways and the development of novel compounds.

02 /Properties
Molecular weight187.58
Linear formulaClC6H3(NO2)OCH3
Assay98%
Application4-chloro-3-nitroanisole is used to synthesize a group of derivatives of 7-methanesulfonylamino-6-phenoxychromone at the pyrone and phenoxy rings.
Melting point41-43 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Flash point110 °C / 230 °F
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
10298-80-3
MDL number
MFCD00007077
PubChem substance
24847280
Beilstein registry
640872
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Chloro-3-nitroanisole used for?

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4-Chloro-3-nitroanisole is used as a building block in organic synthesis, notably for the preparation of derivatives of 7-methanesulfonylamino-6-phenoxychromone.

What is the CAS number and chemical formula for 4-Chloro-3-nitroanisole?

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The CAS number is 10298-80-3 and the chemical formula is ClC6H3(NO2)OCH3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 4-Chloro-3-nitroanisole with an assay of 98%. We do not represent this product as USP, BP, or EP grade.

How should 4-Chloro-3-nitroanisole be handled safely?

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Based on its GHS classification, 4-Chloro-3-nitroanisole is an irritant. Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn. Ensure adequate ventilation to avoid inhalation.

Can Tech Serve Solutions export 4-Chloro-3-nitroanisole?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Chloro-3-nitroanisole.

How can I request a quote or sample?

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Please contact our sales department via the website or telephone to request a quote or sample of 4-Chloro-3-nitroanisole.

Need 4-Chloro-3-nitroanisole in a specific grade or volume?