4-Chloro-3-nitroaniline
4-Chloro-3-nitroaniline (CAS: 635-22-3), with the molecular formula ClC6H3(NO2)NH2 and a molecular weight of 172.57, is a key organic intermediate. This compound serves as a valuable building block in chemical synthesis, particularly in the production of nitrogen-containing compounds. Its specific structure makes it useful for creating more complex molecules across various chemical industries.
- IUPAC
- 4-Amino-1-chloro-2-nitrobenzene
- Synonyms
- 4-Amino-1-chloro-2-nitrobenzene

Chemical Synthesis Intermediate
4-Chloro-3-nitroaniline is widely employed as a precursor in the synthesis of diverse organic molecules. It is particularly useful in the creation of dyes, pigments, and agrochemicals, leveraging its reactive amine and nitro groups.
Pharmaceutical Building Block
This compound functions as a crucial building block in the development of pharmaceutical agents. Its structure can be incorporated into more complex drug molecules, contributing to their therapeutic properties.
Research and Development
In research laboratories, 4-Chloro-3-nitroaniline is utilized for exploring novel chemical reactions and developing new synthetic pathways. Its well-defined chemical properties make it a reliable reagent for scientific investigation.
| Molecular weight | 172.57 |
|---|---|
| Linear formula | ClC6H3(NO2)NH2 |
| Assay | 97% |
| Melting point | 99-101 °C(lit.) |



Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H330Fatal if inhaled
- H373May cause damage to organs through prolonged exposure
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P302IF ON SKIN
| Transport (UN / ADR) | UN 2237 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+,N |
| Risk statements (R) | 26/27/28-33-51/53 |
| Safety statements (S) | 28-36/37-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-3-nitroaniline used for?
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4-Chloro-3-nitroaniline is primarily used as an intermediate in chemical synthesis, including the production of pharmaceuticals, dyes, and agrochemicals. It also serves as a building block in research and development.
What are the CAS number and formula for 4-Chloro-3-nitroaniline?
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The CAS number for 4-Chloro-3-nitroaniline is 635-22-3, and its molecular formula is ClC6H3(NO2)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-3-nitroaniline with an assay of 97%. This product is typically supplied for technical or research purposes and is not represented as USP, BP, or EP grade.
How should 4-Chloro-3-nitroaniline be handled?
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4-Chloro-3-nitroaniline is a hazardous substance. Handle with extreme caution, using appropriate personal protective equipment (gloves, safety glasses, respiratory protection) in a well-ventilated area, to avoid contact and inhalation, as it is toxic by ingestion, skin contact, and inhalation, and may cause organ damage with prolonged exposure.
How is 4-Chloro-3-nitroaniline packed and shipped?
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Tech Serve Solutions professionally packs and ships chemicals globally, adhering to all relevant transport regulations for hazardous materials. Specifically, this compound is classified under UN 2237, Hazard Class 6.1, Packing Group III.
How can I request a quote or sample for 4-Chloro-3-nitroaniline?
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To request a quote or a sample of 4-Chloro-3-nitroaniline, please visit the Tech Serve Solutions website or contact our sales team directly.
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