4-Chloro-2,6-difluorobenzaldehyde
4-Chloro-2,6-difluorobenzaldehyde (CAS: 252004-45-8; C7H3ClF2O) is a fluorinated aromatic aldehyde with a molecular weight of 176.55 g/mol. This compound serves as a valuable building block in organic synthesis. Its specific structural features make it a useful intermediate for the preparation of more complex molecules, particularly within the pharmaceutical and agrochemical research sectors, owing to the presence of reactive aldehyde and halogen functionalities.
- Synonyms
- C7H3ClF2O

Intermediate in Pharmaceutical Synthesis
Used as a key building block in the development of novel pharmaceutical compounds. The aldehyde group allows for various derivatizations, while the fluoro and chloro substituents can influence pharmacokinetic properties.
Precursor for Agrochemical Development
Applied in the synthesis of new agrochemicals. The difluorinated phenyl ring can impart desirable characteristics such as enhanced stability and efficacy to potential pesticides or herbicides.
Research and Development
Employed in academic and industrial research laboratories for the exploration of new chemical entities and synthetic methodologies. Facilitates the study of structure-activity relationships due to its defined substitution pattern.
| Molecular weight | 176.55 |
|---|---|
| Empirical formula | C7H3ClF2O |
| Assay | 97% |
| Melting point | 68-73 °C |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Chloro-2,6-difluorobenzaldehyde primarily used for?
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4-Chloro-2,6-difluorobenzaldehyde (CAS: 252004-45-8) is primarily used as a building block in organic synthesis, particularly for the development of pharmaceutical intermediates and agrochemicals.
What are the CAS number and molecular formula for this compound?
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The CAS number is 252004-45-8, and the molecular formula is C7H3ClF2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Chloro-2,6-difluorobenzaldehyde with an assay of 97%. This is a technical/research grade material, and we do not represent it as USP, BP, or EP grade.
How should 4-Chloro-2,6-difluorobenzaldehyde be handled safely?
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This compound is classified as toxic if swallowed and causes skin and eye irritation, and may cause respiratory irritation (H301, H315, H319, H335). Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the safety data sheet for detailed handling instructions.
How is 4-Chloro-2,6-difluorobenzaldehyde packed and shipped?
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Products are packed and shipped according to international regulations for hazardous materials. For 4-Chloro-2,6-difluorobenzaldehyde (UN 2811, 6.1/PGIII), specific packaging compliant with transport regulations is used for export.
How can I request a sample or quote for 4-Chloro-2,6-difluorobenzaldehyde?
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Please contact our sales team via the website or by phone to request a sample or a formal quotation for 4-Chloro-2,6-difluorobenzaldehyde.
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