4-Butoxyphenylboronic acid
4-Butoxyphenylboronic acid (CAS: 105365-51-3; Formula: C10H15BO3; MW: 194.04) is a versatile aryl boronic acid derivative. It functions as a key reactant in various organic synthesis pathways. Its primary applications include Suzuki-Miyaura cross-coupling reactions, condensation reactions, and the synthesis of complex organic molecules such as azobenzene-functionalized compounds and fluorescent diketopyrrolopyrrole derivatives. Supplied by Tech Serve Solutions for research and development purposes.

Suzuki-Miyaura Cross-Coupling Reactions
4-Butoxyphenylboronic acid is a valuable substrate for palladium-catalyzed Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds with aryl or vinyl halides and pseudohalides. This reaction is widely used in the synthesis of biaryl compounds and other complex organic structures.
Synthesis of Functionalised Compounds
The compound serves as a building block for the synthesis of azobenzene-functionalized materials and highly fluorescent diketopyrrolopyrrole derivatives. These applications are crucial in the development of advanced materials and dyes.
Condensation Reactions
It participates effectively in condensation reactions, contributing to the construction of diverse organic molecules. These reactions are fundamental in organic synthesis for creating new chemical entities.
Rhodium and Copper Catalysis
This boronic acid is also employed in rhodium-catalyzed Suzuki-type cross-couplings and copper-catalyzed asymmetric conjugate reductions, expanding its utility in sophisticated catalytic transformations.
| Molecular weight | 194.04 |
|---|---|
| Linear formula | C6H4OCH2CH2CH2CH3B(OH)2 |
| Application | Reactant for:• Suzuki-Miyaura cross-coupling reactions1• Condensation reactions2• Synthesis of azobenzene-functionalized compounds3• Preparation of highly fluorescent diketopyrrolopyrrole derivatives4• Rhodium-catalyzed Suzuki-type cross-coupling5• Copper-catalyzed asymmetric conjugate reduction of coumarins6 |
| Melting point | 106-108 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Butoxyphenylboronic acid used for?
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4-Butoxyphenylboronic acid is used as a reactant in Suzuki-Miyaura cross-coupling reactions, condensation reactions, and for the synthesis of azobenzene-functionalized compounds and fluorescent diketopyrrolopyrrole derivatives. It is also applied in rhodium-catalyzed Suzuki-type cross-coupling and copper-catalyzed asymmetric conjugate reduction of coumarins.
What is the CAS number and chemical formula for 4-Butoxyphenylboronic acid?
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The CAS number is 105365-51-3, and the linear chemical formula is C10H15BO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Butoxyphenylboronic acid as a research or technical grade chemical. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade, as specific purity assays are not detailed in the product data.
What are the safety precautions when handling 4-Butoxyphenylboronic acid?
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When handling 4-Butoxyphenylboronic acid, it is essential to use safety equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for comprehensive handling information and hazard details.
How is 4-Butoxyphenylboronic acid packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals in compliance with international regulations, ensuring product integrity and safety during transit. Specific packaging details are available upon request.
How can I request a sample or a quote for 4-Butoxyphenylboronic acid?
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To request a sample or a quote for 4-Butoxyphenylboronic acid, please contact our sales team through the website or by phone. Our team will assist you with your inquiry promptly.
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