4-Bromo-2-thiophenecarboxaldehyde
4-Bromo-2-thiophenecarboxaldehyde (CAS: 18791-75-8), with the molecular formula C5H3BrOS and a molecular weight of 191.05 g/mol, is a key organic building block. This halogenated thiophene derivative serves as a valuable intermediate in organic synthesis. Its aldehyde functionality and bromine substituent allow for diverse chemical transformations, making it useful in the preparation of more complex heterocyclic compounds and functionalised molecules for research and development.
Synthesis of Tetrahydroisoquinolinones
4-Bromo-2-thiophenecarboxaldehyde acts as a crucial building block in the multi-step synthesis of tetrahydroisoquinolinone derivatives, contributing to the formation of novel molecular scaffolds.
Preparation of Triazole Derivatives
This compound is utilised in the synthesis of specific heterocyclic systems, such as 3-[(4-bromo-2-thienyl)methylenehydrazinocarbonyl]-1H-1,2,4-triazole, showcasing its utility in constructing nitrogen-containing heterocycles.
General Organic Synthesis Intermediate
As a functionalised thiophene aldehyde, it is employed as a versatile intermediate in various organic chemistry research and development projects, enabling the introduction of the bromothiophene moiety into target molecules.
| Molecular weight | 191.05 |
|---|---|
| Empirical formula | C5H3BrOS |
| Assay | 90% |
| Boiling point | 114-115 °C/11 mmHg(lit.) |
| Storage temperature | 2-8°C |
| Application | 4-Bromo-2-thiophenecarboxaldehyde has been used:• as building block for the synthesis of tetrahydroisoquinolinones1• in the synthesis of 3-[(4-bromo-2-thienyl)methylenehydrazinocarbonyl]-1H-1,2,4-triazole2 |
| Melting point | 44-46 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2-thiophenecarboxaldehyde used for?
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4-Bromo-2-thiophenecarboxaldehyde is used as a building block in organic synthesis, including the preparation of tetrahydroisoquinolinones and specific triazole derivatives.
What is the CAS number and molecular formula for 4-Bromo-2-thiophenecarboxaldehyde?
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The CAS number is 18791-75-8, and the molecular formula is C5H3BrOS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-2-thiophenecarboxaldehyde with an assay of 90%. We do not represent this product as USP, BP, EP or any other pharmacopoeia grade.
How should 4-Bromo-2-thiophenecarboxaldehyde be handled?
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Handle 4-Bromo-2-thiophenecarboxaldehyde with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter if necessary. It has a flash point of 113 °C (235.4 °F).
How is 4-Bromo-2-thiophenecarboxaldehyde packed, shipped, and exported?
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This chemical is typically stored at 2-8°C. TSS is a specialist global supplier and exporter of fine chemicals, handling all aspects of secure and compliant international shipping.
How can I request a sample or quote for 4-Bromo-2-thiophenecarboxaldehyde?
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Please contact our sales team via the website to request a sample or a quotation for 4-Bromo-2-thiophenecarboxaldehyde.
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