4-Bromo-2-methylpyridine
4-Bromo-2-methylpyridine (CAS: 22282-99-1) is a halogenated pyridine derivative with the molecular formula C6H6BrN and a molecular weight of 172.02 g/mol. This compound serves as a valuable building block in organic synthesis. It is particularly utilised as a starting material for the creation of crown-ester-bipyridines and viologens through various coupling, oxidation, and esterification reactions. Available at 96% purity, it is suitable for research and chemical synthesis applications.
Synthesis of Bipyridines
4-Bromo-2-methylpyridine acts as a key precursor in synthesising substituted bipyridines. These compounds are often incorporated into more complex molecular architectures, such as crown-ester-bipyridines, through reductive coupling reactions.
Viologen Synthesis
This brominated pyridine derivative is employed in the preparation of viologens. Via side chain oxidation and subsequent esterification, it contributes to the formation of these electroactive organic compounds.
Halogenated Heterocycle Intermediate
As a member of the halogenated heterocycles family, 4-Bromo-2-methylpyridine is a versatile intermediate for introducing pyridyl moieties into various organic molecules during complex chemical syntheses.
| Molecular weight | 172.02 |
|---|---|
| Empirical formula | C6H6BrN |
| Assay | 96% |
| Density | 1.450 g/mL at 25 °C |
| Refractive index | n20/D 1.556 |
| Application | Starting material used in a synthesis of crown-ester-bipyridines and viologens via sodium or nickel reductive coupling, side chain oxidation and esterification.1 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 78 °C / 172.4 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-36/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2-methylpyridine used for?
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4-Bromo-2-methylpyridine is primarily used as a starting material in organic synthesis for preparing compounds such as crown-ester-bipyridines and viologens through reactions including reductive coupling, side chain oxidation, and esterification.
What are the CAS number and formula for 4-Bromo-2-methylpyridine?
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The CAS number for 4-Bromo-2-methylpyridine is 22282-99-1, and its molecular formula is C6H6BrN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-2-methylpyridine with a purity of 96%. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
What are the main safety hazards associated with 4-Bromo-2-methylpyridine?
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4-Bromo-2-methylpyridine is classified as Danger. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, face shields, and gloves, should be used. Refer to the Safety Data Sheet for full details.
How is 4-Bromo-2-methylpyridine packed and shipped?
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This chemical is packed and shipped according to international regulations for hazardous materials. For detailed information on packaging and export procedures, please contact our sales department.
How can I request a sample or a quote for 4-Bromo-2-methylpyridine?
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To request a sample or obtain a quote, please visit the product page on the Tech Serve Solutions website and use the 'Request Quote' or 'Sample Request' forms, or contact our customer service directly.
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