4-Bromo-2,5-difluorobenzenesulfonyl chloride
4-Bromo-2,5-difluorobenzenesulfonyl chloride (CAS: 207974-14-9) is a fluorinated organic compound with the molecular formula C6H2BrClF2O2S and a molecular weight of 291.50 g/mol. This reactive sulfonyl chloride derivative serves as a valuable building block in organic synthesis. Its specific structure, featuring bromine and fluorine substituents alongside the sulfonyl chloride group, enables diverse chemical transformations, particularly in the development of novel pharmaceuticals and agrochemicals.
- Synonyms
- C6H2BrClF2O2S

Organic Synthesis Intermediate
Utilised as a key intermediate in complex organic synthesis pathways. Its reactive sulfonyl chloride moiety readily participates in substitution reactions, allowing for the introduction of the 4-bromo-2,5-difluorobenzenesulfonyl group into various molecular frameworks.
Pharmaceutical Research and Development
Serves as a building block for the synthesis of potential drug candidates. The incorporation of fluorine and bromine atoms can influence pharmacokinetic properties such as metabolic stability and lipophilicity.
Agrochemical Synthesis
Employed in the creation of new agrochemical compounds. The unique electronic and steric properties conferred by the substituents can contribute to enhanced biological activity or selectivity in crop protection agents.
Materials Science
Potentially used in the development of specialised materials where its unique chemical structure can impart desired properties, such as in the synthesis of functional polymers or advanced organic materials.
| Molecular weight | 291.50 |
|---|---|
| Empirical formula | C6H2BrClF2O2S |
| Assay | 97% |
| Melting point | 38-42 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-2,5-difluorobenzenesulfonyl chloride used for?
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4-Bromo-2,5-difluorobenzenesulfonyl chloride is primarily used as a building block in organic synthesis, particularly in the research and development of pharmaceuticals and agrochemicals.
What is the CAS number and formula for 4-Bromo-2,5-difluorobenzenesulfonyl chloride?
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The CAS number is 207974-14-9 and the empirical formula is C6H2BrClF2O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-2,5-difluorobenzenesulfonyl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 4-Bromo-2,5-difluorobenzenesulfonyl chloride be handled?
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This compound is classified as corrosive and causes severe skin burns and eye damage (H314). Handling requires appropriate personal protective equipment including eyeshields, face shields, gloves, and respiratory protection (e.g., N100 respirators or P3 filters). Work should be conducted in a well-ventilated area.
How is 4-Bromo-2,5-difluorobenzenesulfonyl chloride packed, shipped, and exported?
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Tech Serve Solutions professionally packs and ships chemicals globally, adhering to all relevant transport regulations. This compound is shipped under UN 3261, Class 8, Packing Group III.
How can I request a sample or quote for 4-Bromo-2,5-difluorobenzenesulfonyl chloride?
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To request a sample or a quote, please contact our sales team via the website or direct email, providing the product name and CAS number (207974-14-9).
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