4-Benzyloxyindole
4-Benzyloxyindole (CAS 20289-26-3) is a heterocyclic organic compound with the molecular formula C15H13NO and a molecular weight of 223.27 g/mol. Supplied at 98% purity, this indole derivative serves as a valuable building block in chemical synthesis. Its applications include the preparation of complex molecules such as oxopyrrolidine analogs, intermediates for medicinal chemistry, and potential therapeutic agents like HCV inhibitors and cannabinoid receptor ligands.
- IUPAC
- NSC 92539
Synthesis of Oxopyrrolidine Analogs
4-Benzyloxyindole acts as a reactant for the regioselective synthesis of oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition, enabling access to novel cyclic structures.
Medicinal Chemistry Intermediates
This compound is utilized in the preparation of indoles through Bartoli reductive cyclization, yielding intermediates critical for medicinal chemistry research and drug discovery.
Development of PET Imaging Agents
It serves as a reactant in the synthesis of carbon-11-labeled 4-aryl-4H-chromenes, which are investigated as positron emission tomography (PET) agents for imaging apoptosis in cancer.
Preparation of HCV Inhibitors
4-Benzyloxyindole is employed as a reactant in the synthetic pathways leading to the preparation of compounds with potential activity as Hepatitis C Virus (HCV) inhibitors.
Synthesis of Cannabinoid Receptor Ligands
This indole derivative is a key reactant for preparing indol-3-yl tetramethylcyclopropyl ketones, which are explored as ligands for the CB2 cannabinoid receptor.
| Molecular weight | 223.27 |
|---|---|
| Empirical formula | C15H13NO |
| Assay | 98% |
| Application | • Reactant for regioselective synthesis of oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition• Reactant for preparation of indoles by Bartoli reductive cyclization as useful intermediates in medicinal chemistry research• Reactant for synthesis of carbon-11-labeled 4-aryl-4H-chromenes as new PET agents for imaging of apoptosis in cancer• Reactant for preparation of HCV inhibitors• Reactant for preparation of indol-3-yl tetramethylcyclopropyl ketones as CB2 cannabinoid receptor ligands• Reactant for preparation of 4-aryl-4H-chromenes as apoptosis inducers |
| Melting point | 57-61 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Benzyloxyindole used for?
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4-Benzyloxyindole is used as a building block in chemical synthesis, particularly for preparing oxopyrrolidine analogs, medicinal chemistry intermediates, PET imaging agents, HCV inhibitors, and cannabinoid receptor ligands.
What is the CAS number and formula for 4-Benzyloxyindole?
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The CAS number for 4-Benzyloxyindole is 20289-26-3, and its molecular formula is C15H13NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Benzyloxyindole with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 4-Benzyloxyindole be handled?
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4-Benzyloxyindole is a Warning chemical that causes skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with a dust mask type N95 (US), eyeshields, and gloves. Ensure good ventilation. P261-P305 + P351 + P338.
Is 4-Benzyloxyindole a controlled substance?
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The provided data does not indicate that 4-Benzyloxyindole is a controlled substance.
How is 4-Benzyloxyindole shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific shipping and export details for 4-Benzyloxyindole can be obtained upon request.
How can I request a sample or quote for 4-Benzyloxyindole?
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To request a sample or a quote for 4-Benzyloxyindole, please contact the Tech Serve Solutions sales team through our official channels.
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