4-Amino-3,5-dichlorobenzonitrile
4-Amino-3,5-dichlorobenzonitrile (CAS 78473-00-4), with the molecular formula C7H4Cl2N2 and a molecular weight of 187.03 g/mol, is a key organic building block. This compound is frequently employed in chemical synthesis, particularly in the development of new molecules. Its structure, featuring amino, cyano, and chloro substituents on a benzene ring, makes it a versatile intermediate for various research and development applications in areas such as pharmaceuticals and materials science.
- Synonyms
- H2NC6H2(Cl)2CN

Chemical Synthesis Intermediate
4-Amino-3,5-dichlorobenzonitrile serves as a valuable intermediate in organic synthesis. Its functional groups allow for diverse chemical transformations, facilitating the construction of more complex molecular architectures.
Research and Development
This compound is utilised in R&D settings for the exploration of novel chemical entities. Its specific structure may be of interest for applications in areas like medicinal chemistry and agrochemical research.
Building Block for Heterocycles
The presence of the nitrile and amino groups, along with the dichlorinated aromatic ring, makes this compound a potential precursor for the synthesis of various heterocyclic compounds, which are prevalent in pharmaceuticals.
| Molecular weight | 187.03 |
|---|---|
| Linear formula | H2NC6H2(Cl)2CN |
| Assay | 97% |
| Melting point | 116-120 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H317May cause an allergic skin reaction
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Amino-3,5-dichlorobenzonitrile used for?
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4-Amino-3,5-dichlorobenzonitrile is primarily used as a building block in chemical synthesis and for research and development purposes, potentially in areas like medicinal chemistry and materials science.
What is the CAS number and formula for 4-Amino-3,5-dichlorobenzonitrile?
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The CAS number is 78473-00-4 and the linear formula is H2NC6H2(Cl)2CN.
What grade and purity does Tech Serve Solutions supply for 4-Amino-3,5-dichlorobenzonitrile?
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Tech Serve Solutions supplies 4-Amino-3,5-dichlorobenzonitrile with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
What are the primary safety concerns when handling 4-Amino-3,5-dichlorobenzonitrile?
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This compound is classified as harmful if swallowed (H302), harmful in contact with skin (H312), harmful if inhaled (H332), and may cause an allergic skin reaction (H317). Handling requires appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves. Ensure adequate ventilation.
How is 4-Amino-3,5-dichlorobenzonitrile typically packed and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, offering this product in various quantities suitable for international shipment.
How can I request a quote or sample for 4-Amino-3,5-dichlorobenzonitrile?
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To request a quote or sample, please contact our sales team through the website or by phone, referencing the product name and CAS number 78473-00-4.
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